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Inhaled Steroids Modulate Extracellular Matrix Composition in Bronchial Biopsies of COPD Patients: A Randomized, Controlled Trial

RATIONALE: Smoking and inflammation contribute to the pathogenesis of chronic obstructive pulmonary disease (COPD), which involves changes in extracellular matrix. This is thought to contribute to airway remodeling and airflow obstruction. We have previously observed that long-term treatment with in...

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Detalles Bibliográficos
Autores principales:	Kunz, Lisette I. Z., Strebus, Jolanda, Budulac, Simona E., Lapperre, Therese S., Sterk, Peter J., Postma, Dirkje S., Mauad, Thais, Timens, Wim, Hiemstra, Pieter S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646783/ https://www.ncbi.nlm.nih.gov/pubmed/23667615 http://dx.doi.org/10.1371/journal.pone.0063430

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