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Characterization of the Complete Uric Acid Degradation Pathway in the Fungal Pathogen Cryptococcus neoformans
Degradation of purines to uric acid is generally conserved among organisms, however, the end product of uric acid degradation varies from species to species depending on the presence of active catabolic enzymes. In humans, most higher primates and birds, the urate oxidase gene is non-functional and...
Autores principales: | Lee, I. Russel, Yang, Liting, Sebetso, Gaseene, Allen, Rebecca, Doan, Thi H. N., Blundell, Ross, Lui, Edmund Y. L., Morrow, Carl A., Fraser, James A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646786/ https://www.ncbi.nlm.nih.gov/pubmed/23667704 http://dx.doi.org/10.1371/journal.pone.0064292 |
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