Impairment of Mitochondria in Adult Mouse Brain Overexpressing Predominantly Full-Length, N-Terminally Acetylated Human α-Synuclein

While most forms of Parkinson’s Disease (PD) are sporadic in nature, a small percentage of PD have genetic causes as first described for dominant, single base pair changes as well as duplication and triplication in the α-synuclein gene. The α-synuclein gene encodes a 140 amino acid residue protein t...

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Detalles Bibliográficos
Autores principales: Sarafian, Theodore A., Ryan, Christopher M., Souda, Puneet, Masliah, Eliezer, Kar, Upendra K., Vinters, Harry V., Mathern, Gary W., Faull, Kym F., Whitelegge, Julian P., Watson, Joseph B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646806/
https://www.ncbi.nlm.nih.gov/pubmed/23667637
http://dx.doi.org/10.1371/journal.pone.0063557

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