Diversity of T Cell Epitopes in Plasmodium falciparum Circumsporozoite Protein Likely Due to Protein-Protein Interactions

Circumsporozoite protein (CS) is a leading vaccine antigen for falciparum malaria, but is highly polymorphic in natural parasite populations. The factors driving this diversity are unclear, but non-random assortment of the T cell epitopes TH2 and TH3 has been observed in a Kenyan parasite population...

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Detalles Bibliográficos
Autores principales: Aragam, Nagesh R., Thayer, Kelly M., Nge, Nabi, Hoffman, Irving, Martinson, Francis, Kamwendo, Debbie, Lin, Feng-Chang, Sutherland, Colin, Bailey, Jeffrey A., Juliano, Jonathan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646838/
https://www.ncbi.nlm.nih.gov/pubmed/23667476
http://dx.doi.org/10.1371/journal.pone.0062427

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