Identification of 5-Iodotubercidin as a Genotoxic Drug with Anti-Cancer Potential

Tumor suppressor p53, which is activated by various stress and oncogene activation, is a target for anti-cancer drug development. In this study, by screening panels of protein kinase inhibitors and protein phosphatase inhibitors, we identified 5-Iodotubercidin as a strong p53 activator. 5-Iodotuberc...

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Detalles Bibliográficos
Autores principales: Zhang, Xin, Jia, Deyong, Liu, Huijuan, Zhu, Na, Zhang, Wei, Feng, Jun, Yin, Jun, Hao, Bin, Cui, Daxiang, Deng, Yuezhen, Xie, Dong, He, Lin, Li, Baojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646850/
https://www.ncbi.nlm.nih.gov/pubmed/23667485
http://dx.doi.org/10.1371/journal.pone.0062527

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