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Engineering T Cell Function Using Chimeric Antigen Receptors Identified Using a DNA Library Approach
Genetic engineering of cellular function holds much promise for the treatment of a variety of diseases including gene deficiencies and cancer. However, engineering the full complement of cellular functions can be a daunting genetic exercise since many molecular triggers need to be activated to achie...
Autores principales: | Duong, Connie P. M., Westwood, Jennifer A., Yong, Carmen S. M., Murphy, Amanda, Devaud, Christel, John, Liza B., Darcy, Phillip K., Kershaw, Michael H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646939/ https://www.ncbi.nlm.nih.gov/pubmed/23667569 http://dx.doi.org/10.1371/journal.pone.0063037 |
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