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Presenilin Promotes Dietary Copper Uptake

Dietary copper is essential for multicellular organisms. Copper is redox active and required as a cofactor for enzymes such as the antioxidant Superoxide Dismutase 1 (SOD1). Copper dyshomeostasis has been implicated in Alzheimer’s disease. Mutations in the presenilin genes encoding PS1 and PS2 are m...

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Detalles Bibliográficos
Autores principales:	Southon, Adam, Greenough, Mark A., Ganio, George, Bush, Ashley I., Burke, Richard, Camakaris, James
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646984/ https://www.ncbi.nlm.nih.gov/pubmed/23667524 http://dx.doi.org/10.1371/journal.pone.0062811

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