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Tauroursodeoxycholic Acid Mitigates High Fat Diet-Induced Cardiomyocyte Contractile and Intracellular Ca(2+) Anomalies

OBJECTIVES: The endoplasmic reticulum (ER) chaperone tauroursodeoxycholic acid (TUDCA) has exhibited promises in the treatment of obesity, although its impact on obesity-induced cardiac dysfunction is unknown. This study examined the effect of TUDCA on cardiomyocyte function in high-fat diet-induced...

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Detalles Bibliográficos
Autores principales: Turdi, Subat, Hu, Nan, Ren, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647067/
https://www.ncbi.nlm.nih.gov/pubmed/23667647
http://dx.doi.org/10.1371/journal.pone.0063615