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A Solitary Fibrous Tumor with Giant Cells in the Lacrimal Gland: A Case Study
Orbital solitary fibrous tumor (SFT) has recently been proposed as the encompassing terminology for hemangiopericytoma, giant cell angiofibroma (GCAF), and fibrous histiocytoma of the orbit. The lacrimal gland is a very rare location for both SFT and GCAF. A 39-year-old man presented with a painless...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Pathologists and The Korean Society for Cytopathology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647128/ https://www.ncbi.nlm.nih.gov/pubmed/23667375 http://dx.doi.org/10.4132/KoreanJPathol.2013.47.2.158 |
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author | Son, Da Hye Yoo, Su Hyun Sa, Ho-Seok Cho, Kyung-Ja |
author_facet | Son, Da Hye Yoo, Su Hyun Sa, Ho-Seok Cho, Kyung-Ja |
author_sort | Son, Da Hye |
collection | PubMed |
description | Orbital solitary fibrous tumor (SFT) has recently been proposed as the encompassing terminology for hemangiopericytoma, giant cell angiofibroma (GCAF), and fibrous histiocytoma of the orbit. The lacrimal gland is a very rare location for both SFT and GCAF. A 39-year-old man presented with a painless left upper eyelid mass. An orbital computed tomography scan identified a 1.1 cm-sized well-defined nodule located in the left lacrimal gland. He underwent a mass excision. Histopathologic examination showed a proliferation of relatively uniform spindle cells with a patternless or focally storiform pattern. Dilated vessels were prominent, but angiectoid spaces lined with giant cells were absent. Floret-type giant cells were mostly scattered in the periphery. The tumor was immunoreactive for CD34 and CD99, but negative for smooth muscle actin and S-100 protein. This is the first Korean case of SFT of the lacrimal gland with overlapping features of GCAF, suggesting a close relationship between the two entities. |
format | Online Article Text |
id | pubmed-3647128 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | The Korean Society of Pathologists and The Korean Society for Cytopathology |
record_format | MEDLINE/PubMed |
spelling | pubmed-36471282013-05-10 A Solitary Fibrous Tumor with Giant Cells in the Lacrimal Gland: A Case Study Son, Da Hye Yoo, Su Hyun Sa, Ho-Seok Cho, Kyung-Ja Korean J Pathol Case Study Orbital solitary fibrous tumor (SFT) has recently been proposed as the encompassing terminology for hemangiopericytoma, giant cell angiofibroma (GCAF), and fibrous histiocytoma of the orbit. The lacrimal gland is a very rare location for both SFT and GCAF. A 39-year-old man presented with a painless left upper eyelid mass. An orbital computed tomography scan identified a 1.1 cm-sized well-defined nodule located in the left lacrimal gland. He underwent a mass excision. Histopathologic examination showed a proliferation of relatively uniform spindle cells with a patternless or focally storiform pattern. Dilated vessels were prominent, but angiectoid spaces lined with giant cells were absent. Floret-type giant cells were mostly scattered in the periphery. The tumor was immunoreactive for CD34 and CD99, but negative for smooth muscle actin and S-100 protein. This is the first Korean case of SFT of the lacrimal gland with overlapping features of GCAF, suggesting a close relationship between the two entities. The Korean Society of Pathologists and The Korean Society for Cytopathology 2013-04 2013-04-24 /pmc/articles/PMC3647128/ /pubmed/23667375 http://dx.doi.org/10.4132/KoreanJPathol.2013.47.2.158 Text en © 2013 The Korean Society of Pathologists/The Korean Society for Cytopathology http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Study Son, Da Hye Yoo, Su Hyun Sa, Ho-Seok Cho, Kyung-Ja A Solitary Fibrous Tumor with Giant Cells in the Lacrimal Gland: A Case Study |
title | A Solitary Fibrous Tumor with Giant Cells in the Lacrimal Gland: A Case Study |
title_full | A Solitary Fibrous Tumor with Giant Cells in the Lacrimal Gland: A Case Study |
title_fullStr | A Solitary Fibrous Tumor with Giant Cells in the Lacrimal Gland: A Case Study |
title_full_unstemmed | A Solitary Fibrous Tumor with Giant Cells in the Lacrimal Gland: A Case Study |
title_short | A Solitary Fibrous Tumor with Giant Cells in the Lacrimal Gland: A Case Study |
title_sort | solitary fibrous tumor with giant cells in the lacrimal gland: a case study |
topic | Case Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647128/ https://www.ncbi.nlm.nih.gov/pubmed/23667375 http://dx.doi.org/10.4132/KoreanJPathol.2013.47.2.158 |
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