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InterMOD: integrated data and tools for the unification of model organism research
Model organisms are widely used for understanding basic biology, and have significantly contributed to the study of human disease. In recent years, genomic analysis has provided extensive evidence of widespread conservation of gene sequence and function amongst eukaryotes, allowing insights from mod...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647165/ https://www.ncbi.nlm.nih.gov/pubmed/23652793 http://dx.doi.org/10.1038/srep01802 |
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author | Sullivan, Julie Karra, Kalpana Moxon, Sierra A. T. Vallejos, Andrew Motenko, Howie Wong, J. D. Aleksic, Jelena Balakrishnan, Rama Binkley, Gail Harris, Todd Hitz, Benjamin Jayaraman, Pushkala Lyne, Rachel Neuhauser, Steven Pich, Christian Smith, Richard N. Trinh, Quang Cherry, J. Michael Richardson, Joel Stein, Lincoln Twigger, Simon Westerfield, Monte Worthey, Elizabeth Micklem, Gos |
author_facet | Sullivan, Julie Karra, Kalpana Moxon, Sierra A. T. Vallejos, Andrew Motenko, Howie Wong, J. D. Aleksic, Jelena Balakrishnan, Rama Binkley, Gail Harris, Todd Hitz, Benjamin Jayaraman, Pushkala Lyne, Rachel Neuhauser, Steven Pich, Christian Smith, Richard N. Trinh, Quang Cherry, J. Michael Richardson, Joel Stein, Lincoln Twigger, Simon Westerfield, Monte Worthey, Elizabeth Micklem, Gos |
author_sort | Sullivan, Julie |
collection | PubMed |
description | Model organisms are widely used for understanding basic biology, and have significantly contributed to the study of human disease. In recent years, genomic analysis has provided extensive evidence of widespread conservation of gene sequence and function amongst eukaryotes, allowing insights from model organisms to help decipher gene function in a wider range of species. The InterMOD consortium is developing an infrastructure based around the InterMine data warehouse system to integrate genomic and functional data from a number of key model organisms, leading the way to improved cross-species research. So far including budding yeast, nematode worm, fruit fly, zebrafish, rat and mouse, the project has set up data warehouses, synchronized data models, and created analysis tools and links between data from different species. The project unites a number of major model organism databases, improving both the consistency and accessibility of comparative research, to the benefit of the wider scientific community. |
format | Online Article Text |
id | pubmed-3647165 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-36471652013-05-13 InterMOD: integrated data and tools for the unification of model organism research Sullivan, Julie Karra, Kalpana Moxon, Sierra A. T. Vallejos, Andrew Motenko, Howie Wong, J. D. Aleksic, Jelena Balakrishnan, Rama Binkley, Gail Harris, Todd Hitz, Benjamin Jayaraman, Pushkala Lyne, Rachel Neuhauser, Steven Pich, Christian Smith, Richard N. Trinh, Quang Cherry, J. Michael Richardson, Joel Stein, Lincoln Twigger, Simon Westerfield, Monte Worthey, Elizabeth Micklem, Gos Sci Rep Article Model organisms are widely used for understanding basic biology, and have significantly contributed to the study of human disease. In recent years, genomic analysis has provided extensive evidence of widespread conservation of gene sequence and function amongst eukaryotes, allowing insights from model organisms to help decipher gene function in a wider range of species. The InterMOD consortium is developing an infrastructure based around the InterMine data warehouse system to integrate genomic and functional data from a number of key model organisms, leading the way to improved cross-species research. So far including budding yeast, nematode worm, fruit fly, zebrafish, rat and mouse, the project has set up data warehouses, synchronized data models, and created analysis tools and links between data from different species. The project unites a number of major model organism databases, improving both the consistency and accessibility of comparative research, to the benefit of the wider scientific community. Nature Publishing Group 2013-05-08 /pmc/articles/PMC3647165/ /pubmed/23652793 http://dx.doi.org/10.1038/srep01802 Text en Copyright © 2013, Macmillan Publishers Limited. All rights reserved http://creativecommons.org/licenses/by/3.0/ This work is licensed under a Creative Commons Attribution 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by/3.0/ |
spellingShingle | Article Sullivan, Julie Karra, Kalpana Moxon, Sierra A. T. Vallejos, Andrew Motenko, Howie Wong, J. D. Aleksic, Jelena Balakrishnan, Rama Binkley, Gail Harris, Todd Hitz, Benjamin Jayaraman, Pushkala Lyne, Rachel Neuhauser, Steven Pich, Christian Smith, Richard N. Trinh, Quang Cherry, J. Michael Richardson, Joel Stein, Lincoln Twigger, Simon Westerfield, Monte Worthey, Elizabeth Micklem, Gos InterMOD: integrated data and tools for the unification of model organism research |
title | InterMOD: integrated data and tools for the unification of model organism research |
title_full | InterMOD: integrated data and tools for the unification of model organism research |
title_fullStr | InterMOD: integrated data and tools for the unification of model organism research |
title_full_unstemmed | InterMOD: integrated data and tools for the unification of model organism research |
title_short | InterMOD: integrated data and tools for the unification of model organism research |
title_sort | intermod: integrated data and tools for the unification of model organism research |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647165/ https://www.ncbi.nlm.nih.gov/pubmed/23652793 http://dx.doi.org/10.1038/srep01802 |
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