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Therapeutic induction of autophagy to modulate neurodegenerative disease progression
There is accumulating evidence that aggregating, misfolded proteins may have an impact on autophagic function, suggesting that this could be a secondary pathological mechanism in many diseases. In this review, we focus on the role of autophagy in four major neurodegenerative diseases: Alzheimer dise...
Autores principales: | Hochfeld, Warren E, Lee, Shirley, Rubinsztein, David C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647215/ https://www.ncbi.nlm.nih.gov/pubmed/23377551 http://dx.doi.org/10.1038/aps.2012.189 |
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