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Nuclear Transport Modulation Reduces Hypercholesterolemia, Atherosclerosis, and Fatty Liver

BACKGROUND: Elevated cholesterol and triglycerides in blood lead to atherosclerosis and fatty liver, contributing to rising cardiovascular and hepatobiliary morbidity and mortality worldwide. METHODS AND RESULTS: A cell‐penetrating nuclear transport modifier (NTM) reduced hyperlipidemia, atheroscler...

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Detalles Bibliográficos
Autores principales: Liu, Yan, Major, Amy S., Zienkiewicz, Jozef, Gabriel, Curtis L., Veach, Ruth Ann, Moore, Daniel J., Collins, Robert D., Hawiger, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647260/
https://www.ncbi.nlm.nih.gov/pubmed/23563994
http://dx.doi.org/10.1161/JAHA.113.000093