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Cardiac and Renal Protective Effects of Irbesartan via Peroxisome Proliferator‐Activated Receptorγ–Hepatocyte Growth Factor Pathway Independent of Angiotensin II Type 1a Receptor Blockade in Mouse Model of Salt‐Sensitive Hypertension

BACKGROUND: “Aldosterone breakthrough” observed in patients receiving long‐term treatment with angiotensin blockade is strongly associated with increased risk of left ventricular hypertrophy, poor exercise capacity, refractory proteinuria, and declining glomerular filtration rate through the profibr...

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Detalles Bibliográficos
Autores principales:	Kusunoki, Hiroshi, Taniyama, Yoshiaki, Rakugi, Hiromi, Morishita, Ryuichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647265/ https://www.ncbi.nlm.nih.gov/pubmed/23608606 http://dx.doi.org/10.1161/JAHA.113.000103

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