Cargando…

Therapeutic Cardiac‐Targeted Delivery of miR‐1 Reverses Pressure Overload–Induced Cardiac Hypertrophy and Attenuates Pathological Remodeling

BACKGROUND: MicroRNAs (miRNAs) play a key role in the development of heart failure, and recent studies have shown that the muscle‐specific miR‐1 is a key regulator of cardiac hypertrophy. We tested the hypothesis that chronic restoration of miR‐1 gene expression in vivo will regress hypertrophy and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Karakikes, Ioannis, Chaanine, Antoine H., Kang, Soojeong, Mukete, Bertrand N., Jeong, Dongtak, Zhang, Shihong, Hajjar, Roger J., Lebeche, Djamel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647279/ https://www.ncbi.nlm.nih.gov/pubmed/23612897 http://dx.doi.org/10.1161/JAHA.113.000078

Ejemplares similares

Gene Remodeling in Type 2 Diabetic Cardiomyopathy and Its Phenotypic Rescue with SERCA2a
por: Karakikes, Ioannis, et al.
Publicado: (2009)

High-dose chloroquine is metabolically cardiotoxic by inducing lysosomes and mitochondria dysfunction in a rat model of pressure overload hypertrophy
por: Chaanine, Antoine H, et al.
Publicado: (2015)

Nicotinamide Riboside Alleviates Cardiac Dysfunction and Remodeling in Pressure Overload Cardiac Hypertrophy
por: Ma, Sai, et al.
Publicado: (2021)

The Probability of Inconstancy in Assessment of Cardiac Function Post-Myocardial Infarction in Mice
por: Chen, Jiqiu, et al.
Publicado: (2016)

Bezafibrate Attenuates Pressure Overload-Induced Cardiac Hypertrophy and Fibrosis
por: Xu, Si-Chi, et al.
Publicado: (2017)

Innate Immune Cells in Pressure Overload-Induced Cardiac Hypertrophy and Remodeling
por: Liu, Xin, et al.
Publicado: (2021)

Therapeutic Delivery of Pip4k2c‐Modified mRNA Attenuates Cardiac Hypertrophy and Fibrosis in the Failing Heart
por: Magadum, Ajit, et al.
Publicado: (2021)

Mitochondrial Integrity and Function in the Progression of Early Pressure Overload–Induced Left Ventricular Remodeling
por: Chaanine, Antoine H., et al.
Publicado: (2017)

I prostanoid receptor activation attenuates pressure overload-induced cardiac hypertrophy by enhancing glucose oxidation
por: Liu, Qian, et al.
Publicado: (2023)

Ganoderma lucidum polysaccharides attenuates pressure-overload-induced pathological cardiac hypertrophy
por: Zhen, Changlin, et al.
Publicado: (2023)

Effect of Bortezomib on the Efficacy of AAV9.SERCA2a Treatment to Preserve Cardiac Function in a Rat Pressure-Overload Model of Heart Failure
por: Chaanine, Antoine H., et al.
Publicado: (2014)

Microtubule Stabilization in Pressure Overload Cardiac Hypertrophy
por: Sato, Hiroshi, et al.
Publicado: (1997)

Diet-induced obesity promotes altered remodeling and exacerbated cardiac hypertrophy following pressure overload
por: Holzem, Katherine M, et al.
Publicado: (2015)

Anacardic acid attenuates pressure‐overload cardiac hypertrophy through inhibiting histone acetylases
por: Li, Shuo, et al.
Publicado: (2019)

Boron improves cardiac contractility and fibrotic remodeling following myocardial infarction injury
por: Bouchareb, Rihab, et al.
Publicado: (2020)

Olmesartan attenuates pressure-overload- or post-infarction-induced cardiac remodeling in mice
por: Wang, Qiancheng, et al.
Publicado: (2017)

Engineered Circular RNA Sponges Act as miRNA Inhibitors to Attenuate Pressure Overload-Induced Cardiac Hypertrophy
por: Lavenniah, Annadoray, et al.
Publicado: (2020)

Cardiac Expression of Factor X Mediates Cardiac Hypertrophy and Fibrosis in Pressure Overload
por: Guo, Xinji, et al.
Publicado: (2020)

Cardiac Expression of Factor X Mediates Cardiac Hypertrophy and Fibrosis in Pressure Overload
Publicado: (2022)

Reversal of Systemic Hypertension-Associated Cardiac Remodeling in Chronic Pressure Overload Myocardium by Ciglitazone
por: Henderson, Brooke C., et al.
Publicado: (2007)

Long‐term administration of pyridostigmine attenuates pressure overload‐induced cardiac hypertrophy by inhibiting calcineurin signalling
por: Lu, Yi, et al.
Publicado: (2017)

Wnt-C59 Attenuates Pressure Overload-Induced Cardiac Hypertrophy via Interruption of Wnt Pathway
por: Zhao, Zhengbo, et al.
Publicado: (2020)

Sacubitril/valsartan ameliorates cardiac hypertrophy and preserves diastolic function in cardiac pressure overload
por: Nordén, Einar Sjaastad, et al.
Publicado: (2021)

Increased Cardiac Myocyte PDE5 Levels in Human and Murine Pressure Overload Hypertrophy Contribute to Adverse LV Remodeling
por: Vandenwijngaert, Sara, et al.
Publicado: (2013)

IKKi Deficiency Promotes Pressure Overload-Induced Cardiac Hypertrophy and Fibrosis
por: Dai, Jia, et al.
Publicado: (2013)

Intermedin Suppresses Pressure Overload Cardiac Hypertrophy through Activation of Autophagy
por: Chen, HuaLi, et al.
Publicado: (2013)

Effects of miRNA-455 on cardiac hypertrophy induced by pressure overload
por: WU, CHUNTAO, et al.
Publicado: (2015)

Resveratrol as a new inhibitor of immunoproteasome prevents PTEN degradation and attenuates cardiac hypertrophy after pressure overload
por: Chen, Chen, et al.
Publicado: (2018)

Signaling via the Interleukin-10 Receptor Attenuates Cardiac Hypertrophy in Mice During Pressure Overload, but not Isoproterenol Infusion
por: Stafford, Nicholas, et al.
Publicado: (2020)

Preconditioning with Short-Term Dietary Restriction Attenuates Cardiac Oxidative Stress and Hypertrophy Induced by Chronic Pressure Overload
por: Kobara, Miyuki, et al.
Publicado: (2021)

Retracted: Wnt-C59 Attenuates Pressure Overload-Induced Cardiac Hypertrophy via Interruption of Wnt Pathway
por: Zhao, Zhengbo, et al.
Publicado: (2023)

Resistance training attenuates salt overload-induced cardiac remodeling and diastolic dysfunction in normotensive rats
por: Barretti, D.L.M., et al.
Publicado: (2017)

Postnatal Ablation of Foxm1 from Cardiomyocytes Causes Late Onset Cardiac Hypertrophy and Fibrosis without Exacerbating Pressure Overload-Induced Cardiac Remodeling
por: Bolte, Craig, et al.
Publicado: (2012)

Role of CyPA in cardiac hypertrophy and remodeling
por: Cao, Mengfei, et al.
Publicado: (2019)

SUMO1-dependent modulation of SERCA2a in heart failure
por: Kho, Changwon, et al.
Publicado: (2011)

Combination Treatment With Antihypertensive Agents Enhances the Effect of Qiliqiangxin on Chronic Pressure Overload–induced Cardiac Hypertrophy and Remodeling in Male Mice
por: Ye, Yong, et al.
Publicado: (2015)

The Natural Product Zerumbone Suppresses Pressure Overload-Induced Cardiac Dysfunction by Inhibiting Cardiac Hypertrophy and Fibrosis
por: Tojima, Mikuto, et al.
Publicado: (2021)

Growth hormone-releasing hormone attenuates cardiac hypertrophy and improves heart function in pressure overload-induced heart failure
por: Gesmundo, Iacopo, et al.
Publicado: (2017)

IL-12α deficiency attenuates pressure overload-induced cardiac inflammation, hypertrophy, dysfunction, and heart failure progression
por: Bhattarai, Umesh, et al.
Publicado: (2023)

The Anti-Inflammatory Mediator 17(R)-Resolvin D1 Attenuates Pressure Overload-Induced Cardiac Hypertrophy and Fibrosis
por: Wang, Menglong, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_7lq10t5lon2nje5l46sajnds9f