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The high-performance liquid chromatographic fingerprints study of Awei capsules
BACKGROUND: Awei Capusules are Hospital preparation for Hyperlipidemia. It was composed by Awei, Magnoliae Officinalis and Polygonum Bistoral etc. Manufacture and quality standard of Awei Capusules had been studied. Results of animal pharmacodynamic and clinical study all displayed that Awei Capusul...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647397/ https://www.ncbi.nlm.nih.gov/pubmed/23661996 http://dx.doi.org/10.4103/0973-1296.108143 |
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author | Han, Rong Xue, Jie Hua, Erwei Zhou, Longlong |
author_facet | Han, Rong Xue, Jie Hua, Erwei Zhou, Longlong |
author_sort | Han, Rong |
collection | PubMed |
description | BACKGROUND: Awei Capusules are Hospital preparation for Hyperlipidemia. It was composed by Awei, Magnoliae Officinalis and Polygonum Bistoral etc. Manufacture and quality standard of Awei Capusules had been studied. Results of animal pharmacodynamic and clinical study all displayed that Awei Capusules can reduce serum levels of TC, TG, LDL-C, increases HDL-C/TC. It was safe. It could improve hemorrheology and vessel function of blood stasis animal. On the basis of these, we studied on fingerprint of Awei capsule. MATERIALS AND METHODS: The gradient elution method was used for analyzing samples on HPLC. Fingerprint similarity calculation software was used for data analysis. RESULTS: We got a good separation of Awei Capusules peaks. There were 15 peaks in fingerprint of Awei capusles. Gallic acid, magnolol and honokiol were identified. CONCLUSION: HPLC fingerprinting of Awei Capusules can provide to reference. It can control preparations quality of Awei Capusules. |
format | Online Article Text |
id | pubmed-3647397 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-36473972013-05-09 The high-performance liquid chromatographic fingerprints study of Awei capsules Han, Rong Xue, Jie Hua, Erwei Zhou, Longlong Pharmacogn Mag Original Article BACKGROUND: Awei Capusules are Hospital preparation for Hyperlipidemia. It was composed by Awei, Magnoliae Officinalis and Polygonum Bistoral etc. Manufacture and quality standard of Awei Capusules had been studied. Results of animal pharmacodynamic and clinical study all displayed that Awei Capusules can reduce serum levels of TC, TG, LDL-C, increases HDL-C/TC. It was safe. It could improve hemorrheology and vessel function of blood stasis animal. On the basis of these, we studied on fingerprint of Awei capsule. MATERIALS AND METHODS: The gradient elution method was used for analyzing samples on HPLC. Fingerprint similarity calculation software was used for data analysis. RESULTS: We got a good separation of Awei Capusules peaks. There were 15 peaks in fingerprint of Awei capusles. Gallic acid, magnolol and honokiol were identified. CONCLUSION: HPLC fingerprinting of Awei Capusules can provide to reference. It can control preparations quality of Awei Capusules. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3647397/ /pubmed/23661996 http://dx.doi.org/10.4103/0973-1296.108143 Text en Copyright: © Pharmacognosy Magazine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Han, Rong Xue, Jie Hua, Erwei Zhou, Longlong The high-performance liquid chromatographic fingerprints study of Awei capsules |
title | The high-performance liquid chromatographic fingerprints study of Awei capsules |
title_full | The high-performance liquid chromatographic fingerprints study of Awei capsules |
title_fullStr | The high-performance liquid chromatographic fingerprints study of Awei capsules |
title_full_unstemmed | The high-performance liquid chromatographic fingerprints study of Awei capsules |
title_short | The high-performance liquid chromatographic fingerprints study of Awei capsules |
title_sort | high-performance liquid chromatographic fingerprints study of awei capsules |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647397/ https://www.ncbi.nlm.nih.gov/pubmed/23661996 http://dx.doi.org/10.4103/0973-1296.108143 |
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