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Novel Molecular Type of Clostridium difficile in Neonatal Pigs, Western Australia

Clostridium difficile causes neonatal enteritis in piglets; strains of PCR ribotype 078 are most commonly identified. We investigated C. difficile prevalence in piglets in Australia and isolated a novel strain with a unique pathogenicity locus. In a mouse infection model, this strain produced more w...

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Detalles Bibliográficos
Autores principales: Squire, Michele M., Carter, Glen P., Mackin, Kate E., Chakravorty, Anjana, Norén, Torbjörn, Elliott, Briony, Lyras, Dena, Riley, Thomas V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647499/
https://www.ncbi.nlm.nih.gov/pubmed/23697508
http://dx.doi.org/10.3201/eid1905.121062
Descripción
Sumario:Clostridium difficile causes neonatal enteritis in piglets; strains of PCR ribotype 078 are most commonly identified. We investigated C. difficile prevalence in piglets in Australia and isolated a novel strain with a unique pathogenicity locus. In a mouse infection model, this strain produced more weight loss than did a ribotype 078 strain.