Cargando…

Phenotypic Characterization of LEA Rat: A New Rat Model of Nonobese Type 2 Diabetes

Animal models have provided important information for the genetics and pathophysiology of diabetes. Here we have established a novel, nonobese rat strain with spontaneous diabetes, Long-Evans Agouti (LEA) rat derived from Long-Evans (LE) strain. The incidence of diabetes in the males was 10% at 6 mo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Okamura, Tadashi, Pei, Xiang Yuan, Miyoshi, Ichiro, Shimizu, Yukiko, Takanashi-Yanobu, Rieko, Mototani, Yasumasa, Kanai, Takao, Satoh, Jo, Kimura, Noriko, Kasai, Noriyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647576/ https://www.ncbi.nlm.nih.gov/pubmed/23691528 http://dx.doi.org/10.1155/2013/986462

Ejemplares similares

A deletion in the Ctns gene causes renal tubular dysfunction and cystine accumulation in LEA/Tohm rats
por: Shimizu, Yukiko, et al.
Publicado: (2018)

Novel murine model of congenital diabetes: The insulin hyposecretion mouse
por: Nakano, Kenta, et al.
Publicado: (2018)

Genetic locus responsible for diabetic phenotype in the insulin hyposecretion (ihs) mouse
por: Nakano, Kenta, et al.
Publicado: (2020)

Functional validation of tensin2 SH2-PTB domain by CRISPR/Cas9-mediated genome editing
por: MARUSUGI, Kiyoma, et al.
Publicado: (2016)

Deletion of CDKAL1 Affects High-Fat Diet–Induced Fat Accumulation and Glucose-Stimulated Insulin Secretion in Mice, Indicating Relevance to Diabetes
por: Okamura, Tadashi, et al.
Publicado: (2012)

Fatty acid remodeling by LPCAT3 enriches arachidonate in phospholipid membranes and regulates triglyceride transport
por: Hashidate-Yoshida, Tomomi, et al.
Publicado: (2015)

Ventricular Dysfunction in Obese and Nonobese Rats with Metabolic Syndrome
por: Torres-Jacome, Julian, et al.
Publicado: (2022)

Subcellular Localization of Seed-Expressed LEA_4 Proteins Reveals Liquid-Liquid Phase Separation for LEA9 and for LEA48 Homo- and LEA42-LEA48 Heterodimers
por: Ginsawaeng, Orarat, et al.
Publicado: (2021)

Antinociceptive effects of caloric restriction on post-incisional pain in nonobese rats
por: Liu, Yue, et al.
Publicado: (2017)

Henry Charles Lea
Publicado: (1909)

Characterization of Novel Nonobese Type 2 Diabetes Rat Model with Enlarged Kidneys
por: Domon, Ayaka, et al.
Publicado: (2019)

Deletion of CDKAL1 Affects Mitochondrial ATP Generation and First-Phase Insulin Exocytosis
por: Ohara-Imaizumi, Mica, et al.
Publicado: (2010)

Léa: at at the crossroads of science and dreams
por: Antonella Del Rosso
Publicado: (2015)

Lea's chemistry of cement and concrete /
por: Lea, F. M. (Frederick Measham), 1900-
Publicado: (2004)

LEA - The LIL experimental area
por: Rinolfi, L
Publicado: (1997)

LEA: the LIL experimental area
por: Rinolfi, L
Publicado: (1997)

Entre saberes te leas... /
Publicado: (2016)

LEA: the LIL experimental area
por: Rinolfi, L
Publicado: (1997)

Lea’s Series of Medical Epitomes
Publicado: (1904)

Lea’s Series of Medical Epitomes
Publicado: (1905)

Lea’s Series of Medical Epitomes
Publicado: (1911)

LEA13 and LEA30 Are Involved in Tolerance to Water Stress and Stomata Density in Arabidopsis thaliana
por: López-Cordova, Abigael, et al.
Publicado: (2021)

The eSS rat, a nonobese model of disordered glucose and lipid metabolism and fatty liver
por: Daniele, Stella M, et al.
Publicado: (2010)

Lea y piense : compendio de frases sabias /

Group 3 LEA Protein, ZmLEA3, Is Involved in Protection from Low Temperature Stress
por: Liu, Yang, et al.
Publicado: (2016)

Relationship between postprandial endotoxemia in nonobese postmenopausal women and diabetic nonobese postmenopausal women
por: Zaman, Gaffar Sarwar, et al.
Publicado: (2015)

SiLEA14, a novel atypical LEA protein, confers abiotic stress resistance in foxtail millet
por: Wang, Meizhen, et al.
Publicado: (2014)

The Spontaneously Diabetic Torii Rat: An Animal Model of Nonobese Type 2 Diabetes with Severe Diabetic Complications
por: Sasase, Tomohiko, et al.
Publicado: (2013)

Estrogen deprivation aggravates cardiac hypertrophy in nonobese Type 2 diabetic Goto–Kakizaki (GK) rats
por: Apaijai, Nattayaporn, et al.
Publicado: (2017)

Structural properties and enzyme stabilization function of the intrinsically disordered LEA_4 protein TdLEA3 from wheat
por: Koubaa, Sana, et al.
Publicado: (2019)

Identification of the BcLEA Gene Family and Functional Analysis of the BcLEA73 Gene in Wucai (Brassica campestris L.)
por: Jiang, Yueyue, et al.
Publicado: (2023)

The Effect of Lipotoxicity on Renal Dysfunction in a Nonobese Rat Model of Metabolic Syndrome: A Urinary Proteomic Approach
por: Markova, Irena, et al.
Publicado: (2019)

Procedure pour faisceau CMS dans LEA
por: Rinolfi, L
Publicado: (1993)

Procédure pour Faisceau CMS dans LEA
por: Rinolfi, L
Publicado: (1994)

Late Embryogenesis Abundant (LEA) proteins in legumes
por: Battaglia, Marina, et al.
Publicado: (2013)

LEA motifs promote desiccation tolerance in vivo
por: Hibshman, Jonathan D., et al.
Publicado: (2021)

Lea’s Series of Pocket Textbooks: Diseases of Children
Publicado: (1907)

A LEA model peptide protects the function of a red fluorescent protein in the dry state
por: Furuki, Takao, et al.
Publicado: (2018)

LEA polypeptide profiling of recalcitrant and orthodox legume seeds reveals ABI3-regulated LEA protein abundance linked to desiccation tolerance
por: Delahaie, Julien, et al.
Publicado: (2013)

Isolation and characterization of an atypical LEA gene (IpLEA) from Ipomoea pes-caprae conferring salt/drought and oxidative stress tolerance
por: Zheng, Jiexuan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ovpn6c9sad885918m300ffi41c