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The ERK(1/2) Inhibitor U0126 Attenuates Diabetes-Induced Upregulation of MMP-9 and Biomarkers of Inflammation in the Retina

This study was conducted to determine the expression of matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in a time-dependent manner and the effect of extracellular-signal-regulated kinases-1/2 (ERK(1/2)) inhibition on the expressions of MMP-9, TIMP-1, and infla...

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Detalles Bibliográficos
Autores principales: Mohammad, Ghulam, Mairaj Siddiquei, Mohammad, Imtiaz Nawaz, Mohammad, Abu El-Asrar, Ahmed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647581/
https://www.ncbi.nlm.nih.gov/pubmed/23671886
http://dx.doi.org/10.1155/2013/658548