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Deoxycholic Acid as a Modifier of the Permeation of Gliclazide through the Blood Brain Barrier of a Rat

Major problem for diabetic patients represents damage of blood vessels and the oxidative stress of the brain cells due to increased concentration of free radicals and poor nutrition of brain cells. Gliclazide has antioxidative properties and poor blood brain barrier (BBB) penetration. Bile acids are...

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Detalles Bibliográficos
Autores principales: Lalić-Popović, Mladena, Vasović, Velibor, Milijašević, Boris, Goločorbin-Kon, Svetlana, Al-Salami, Hani, Mikov, Momir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647598/
https://www.ncbi.nlm.nih.gov/pubmed/23671878
http://dx.doi.org/10.1155/2013/598603