Virulence of Pertactin-Negative Bordetella pertussis Isolates from Infants, France

Bordetella pertussis isolates that do not express pertactin (PRN) are increasing in regions where acellular pertussis vaccines have been used for >7 years. We analyzed data from France and compared clinical symptoms among infants <6 months old infected by PRN-positive or PRN-negative isolates....

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Detalles Bibliográficos
Autores principales: Bodilis, Hélène, Guiso, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2013
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647673/
https://www.ncbi.nlm.nih.gov/pubmed/23621904
http://dx.doi.org/10.3201/1903.121475
Descripción
Sumario:Bordetella pertussis isolates that do not express pertactin (PRN) are increasing in regions where acellular pertussis vaccines have been used for >7 years. We analyzed data from France and compared clinical symptoms among infants <6 months old infected by PRN-positive or PRN-negative isolates. No major clinical differences were found between the 2 groups.

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