rac-(1S*,4aS*,8aS*)-4a-Hy­droxy-2-methyl­perhydro­spiro­[isoquinoline-4,1′-cyclo­hexa­n]-2′-one

In the title compound, C(15)H(25)NO(2), all three six-membered rings adopt chair conformations. The cyclo­hexane and piperidine rings within the perhydro­isoquinoline are trans–trans fused. The N atom has a trigonal–pyramidal geometry (the sum of the bond angles is 328.0°). The methyl substituent oc...

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Detalles Bibliográficos
Autores principales: Siaka, Sorho, Soldatenkov, Anatoly T., Malkova, Anastasia V., Soldatova, Svetlana A., Khrustalev, Victor N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647829/
https://www.ncbi.nlm.nih.gov/pubmed/23723795
http://dx.doi.org/10.1107/S1600536813007010
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author Siaka, Sorho
Soldatenkov, Anatoly T.
Malkova, Anastasia V.
Soldatova, Svetlana A.
Khrustalev, Victor N.
author_facet Siaka, Sorho
Soldatenkov, Anatoly T.
Malkova, Anastasia V.
Soldatova, Svetlana A.
Khrustalev, Victor N.
author_sort Siaka, Sorho
collection PubMed
description In the title compound, C(15)H(25)NO(2), all three six-membered rings adopt chair conformations. The cyclo­hexane and piperidine rings within the perhydro­isoquinoline are trans–trans fused. The N atom has a trigonal–pyramidal geometry (the sum of the bond angles is 328.0°). The methyl substituent occupies the sterically preferrable equatorial position. In the crystal, mol­ecules form infinite [100] chains via O—H⋯N hydrogen bonds.
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spelling pubmed-36478292013-05-30 rac-(1S*,4aS*,8aS*)-4a-Hy­droxy-2-methyl­perhydro­spiro­[isoquinoline-4,1′-cyclo­hexa­n]-2′-one Siaka, Sorho Soldatenkov, Anatoly T. Malkova, Anastasia V. Soldatova, Svetlana A. Khrustalev, Victor N. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(15)H(25)NO(2), all three six-membered rings adopt chair conformations. The cyclo­hexane and piperidine rings within the perhydro­isoquinoline are trans–trans fused. The N atom has a trigonal–pyramidal geometry (the sum of the bond angles is 328.0°). The methyl substituent occupies the sterically preferrable equatorial position. In the crystal, mol­ecules form infinite [100] chains via O—H⋯N hydrogen bonds. International Union of Crystallography 2013-04-05 /pmc/articles/PMC3647829/ /pubmed/23723795 http://dx.doi.org/10.1107/S1600536813007010 Text en © Siaka et al. 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Siaka, Sorho
Soldatenkov, Anatoly T.
Malkova, Anastasia V.
Soldatova, Svetlana A.
Khrustalev, Victor N.
rac-(1S*,4aS*,8aS*)-4a-Hy­droxy-2-methyl­perhydro­spiro­[isoquinoline-4,1′-cyclo­hexa­n]-2′-one
title rac-(1S*,4aS*,8aS*)-4a-Hy­droxy-2-methyl­perhydro­spiro­[isoquinoline-4,1′-cyclo­hexa­n]-2′-one
title_full rac-(1S*,4aS*,8aS*)-4a-Hy­droxy-2-methyl­perhydro­spiro­[isoquinoline-4,1′-cyclo­hexa­n]-2′-one
title_fullStr rac-(1S*,4aS*,8aS*)-4a-Hy­droxy-2-methyl­perhydro­spiro­[isoquinoline-4,1′-cyclo­hexa­n]-2′-one
title_full_unstemmed rac-(1S*,4aS*,8aS*)-4a-Hy­droxy-2-methyl­perhydro­spiro­[isoquinoline-4,1′-cyclo­hexa­n]-2′-one
title_short rac-(1S*,4aS*,8aS*)-4a-Hy­droxy-2-methyl­perhydro­spiro­[isoquinoline-4,1′-cyclo­hexa­n]-2′-one
title_sort rac-(1s*,4as*,8as*)-4a-hy­droxy-2-methyl­perhydro­spiro­[isoquinoline-4,1′-cyclo­hexa­n]-2′-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647829/
https://www.ncbi.nlm.nih.gov/pubmed/23723795
http://dx.doi.org/10.1107/S1600536813007010
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