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Diethyl 4-(2-meth­oxy­phen­yl)-2,6-di­methyl-1,4-di­hydro­pyridine-3,5-di­carboxyl­ate

In the title compound, C(20)H(25)NO(5), the di­hydro­pyridine ring adopts a flattened boat conformation. The meth­oxy­phenyl ring is almost perpendicular to the mean plane of the pyridine ring [dihedral angle = 88.42 (3)°]. The two carbonyl units adopt a synperiplanar conformation with respect to th...

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Detalles Bibliográficos
Autores principales: Wang, Ke, Wang, Yifeng, Yao, Minjie, Xu, Danqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648309/
https://www.ncbi.nlm.nih.gov/pubmed/23723929
http://dx.doi.org/10.1107/S1600536813009951
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author Wang, Ke
Wang, Yifeng
Yao, Minjie
Xu, Danqian
author_facet Wang, Ke
Wang, Yifeng
Yao, Minjie
Xu, Danqian
author_sort Wang, Ke
collection PubMed
description In the title compound, C(20)H(25)NO(5), the di­hydro­pyridine ring adopts a flattened boat conformation. The meth­oxy­phenyl ring is almost perpendicular to the mean plane of the pyridine ring [dihedral angle = 88.42 (3)°]. The two carbonyl units adopt a synperiplanar conformation with respect to the double bonds in the di­hydro­pyridine ring. In the crystal, mol­ecules are connected by N—H⋯O hydrogen bonds into R (4) (4)(24) tetra­meric rings. A region of disordered electron density, located at the center of four adjacent mol­ecules, was treated with the SQUEEZE routine in PLATON [Spek (2009 ▶). Acta Cryst. D65, 148–155]. It is probably the result of traces of the solvent of crystallization and was not taken into account during the structure refinement.
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spelling pubmed-36483092013-05-30 Diethyl 4-(2-meth­oxy­phen­yl)-2,6-di­methyl-1,4-di­hydro­pyridine-3,5-di­carboxyl­ate Wang, Ke Wang, Yifeng Yao, Minjie Xu, Danqian Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(20)H(25)NO(5), the di­hydro­pyridine ring adopts a flattened boat conformation. The meth­oxy­phenyl ring is almost perpendicular to the mean plane of the pyridine ring [dihedral angle = 88.42 (3)°]. The two carbonyl units adopt a synperiplanar conformation with respect to the double bonds in the di­hydro­pyridine ring. In the crystal, mol­ecules are connected by N—H⋯O hydrogen bonds into R (4) (4)(24) tetra­meric rings. A region of disordered electron density, located at the center of four adjacent mol­ecules, was treated with the SQUEEZE routine in PLATON [Spek (2009 ▶). Acta Cryst. D65, 148–155]. It is probably the result of traces of the solvent of crystallization and was not taken into account during the structure refinement. International Union of Crystallography 2013-04-24 /pmc/articles/PMC3648309/ /pubmed/23723929 http://dx.doi.org/10.1107/S1600536813009951 Text en © Wang et al. 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Wang, Ke
Wang, Yifeng
Yao, Minjie
Xu, Danqian
Diethyl 4-(2-meth­oxy­phen­yl)-2,6-di­methyl-1,4-di­hydro­pyridine-3,5-di­carboxyl­ate
title Diethyl 4-(2-meth­oxy­phen­yl)-2,6-di­methyl-1,4-di­hydro­pyridine-3,5-di­carboxyl­ate
title_full Diethyl 4-(2-meth­oxy­phen­yl)-2,6-di­methyl-1,4-di­hydro­pyridine-3,5-di­carboxyl­ate
title_fullStr Diethyl 4-(2-meth­oxy­phen­yl)-2,6-di­methyl-1,4-di­hydro­pyridine-3,5-di­carboxyl­ate
title_full_unstemmed Diethyl 4-(2-meth­oxy­phen­yl)-2,6-di­methyl-1,4-di­hydro­pyridine-3,5-di­carboxyl­ate
title_short Diethyl 4-(2-meth­oxy­phen­yl)-2,6-di­methyl-1,4-di­hydro­pyridine-3,5-di­carboxyl­ate
title_sort diethyl 4-(2-meth­oxy­phen­yl)-2,6-di­methyl-1,4-di­hydro­pyridine-3,5-di­carboxyl­ate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648309/
https://www.ncbi.nlm.nih.gov/pubmed/23723929
http://dx.doi.org/10.1107/S1600536813009951
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