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A systematic study of the N-glycosylation sites of HIV-1 envelope protein on infectivity and antibody-mediated neutralization

BACKGROUND: Glycans on the human immunodeficiency virus (HIV) envelope glycoprotein (Env) play an important role in viral infection and evasion of neutralization by antibodies. In this study, all 25 potential N-linked glycosylation sites (PNGS) on the HIV-1 CRF07_BC Env, FE, were mutated individuall...

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Detalles Bibliográficos
Autores principales:	Wang, Wenbo, Nie, Jianhui, Prochnow, Courtney, Truong, Carolyn, Jia, Zheng, Wang, Suting, Chen, Xiaojiang S, Wang, Youchun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648360/ https://www.ncbi.nlm.nih.gov/pubmed/23384254 http://dx.doi.org/10.1186/1742-4690-10-14

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