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Monocytes/macrophages support mammary tumor invasivity by co-secreting lineage-specific EGFR ligands and a STAT3 activator
BACKGROUND: Tumor-associated macrophages (TAM) promote malignant progression, yet the repertoire of oncogenic factors secreted by TAM has not been clearly defined. We sought to analyze which EGFR- and STAT3-activating factors are secreted by monocytes/macrophages exposed to tumor cell-secreted facto...
Autores principales: | Vlaicu, Philip, Mertins, Philipp, Mayr, Thomas, Widschwendter, Peter, Ataseven, Beyhan, Högel, Bernhard, Eiermann, Wolfgang, Knyazev, Pjotr, Ullrich, Axel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648435/ https://www.ncbi.nlm.nih.gov/pubmed/23597096 http://dx.doi.org/10.1186/1471-2407-13-197 |
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