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Serum biomarkers for neurofibromatosis type 1 and early detection of malignant peripheral nerve-sheath tumors

BACKGROUND: Neurofibromatosis type 1 (NF1) is a hereditary tumor syndrome characterized by the development of benign nerve-sheath tumors, which transform to malignant peripheral nerve-sheath tumors (MPNST) in about 8 to 13% of patients with NF1. MPNST are invasive sarcomas with extremely poor progno...

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Detalles Bibliográficos
Autores principales:	Park, Su-Jin, Sawitzki, Birgit, Kluwe, Lan, Mautner, Victor F, Holtkamp, Nikola, Kurtz, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648455/ https://www.ncbi.nlm.nih.gov/pubmed/23618374 http://dx.doi.org/10.1186/1741-7015-11-109

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