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Low Concentrations of Metformin Selectively Inhibit CD133(+) Cell Proliferation in Pancreatic Cancer and Have Anticancer Action

Pancreatic cancer is the fourth leading cause of cancer related deaths in the United States. The prognosis remains dismal with little advance in treatment. Metformin is a drug widely used for the treatment of type II diabetes. Recent epidemiologic data revealed that oral administration of metformin...

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Detalles Bibliográficos
Autores principales: Gou, Shanmiao, Cui, Pengfei, Li, Xiangsheng, Shi, Pengfei, Liu, Tao, Wang, Chunyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648476/
https://www.ncbi.nlm.nih.gov/pubmed/23667692
http://dx.doi.org/10.1371/journal.pone.0063969