The 53BP1 Homolog in C. elegans Influences DNA Repair and Promotes Apoptosis in Response to Ionizing Radiation

53BP1 contributes to activation of the G2/M checkpoint downstream of ATM and MDC1 in response to ionizing radiation and promotes nonhomologous end-joining (NHEJ) in mammalian cells. In order to determine whether the cellular activities of 53BP1 are conserved in the model organism C. elegans, we anal...

Descripción completa

Detalles Bibliográficos
Autores principales: Ryu, Jin-Sun, Kang, Sang Jo, Koo, Hyeon-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648578/
https://www.ncbi.nlm.nih.gov/pubmed/23667696
http://dx.doi.org/10.1371/journal.pone.0064028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648578/
https://www.ncbi.nlm.nih.gov/pubmed/23667696
http://dx.doi.org/10.1371/journal.pone.0064028

Ejemplares similares