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A conserved Mediator–CDK8 kinase module association regulates Mediator–RNA polymerase II interaction

The CDK8 kinase module (CKM) is a conserved, dissociable Mediator subcomplex whose component subunits were genetically linked to the RNA polymerase II (RNAPII) carboxy-terminal domain (CTD) and individually recognized as transcriptional repressors before Mediator was identified as a preeminent compl...

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Detalles Bibliográficos
Autores principales: Tsai, Kuang-Lei, Sato, Shigeo, Tomomori-Sato, Chieri, Conaway, Ronald C., Conaway, Joan W., Asturias, Francisco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648612/
https://www.ncbi.nlm.nih.gov/pubmed/23563140
http://dx.doi.org/10.1038/nsmb.2549

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