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Valproic acid upregulates NKG2D ligand expression and enhances susceptibility of human renal carcinoma cells to NK cell-mediated cytotoxicity

INTRODUCTION: We aimed to investigate the effect of valproic acid (VPA) on NKG2D ligand expression in human renal carcinoma cell lines and to investigate the mechanisms. MATERIAL AND METHODS: Different concentrations of VPA from 0.5 mM to 8.0 mM were applied to 786-O and ACHN cell lines, respectivel...

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Detalles Bibliográficos
Autores principales:	Yang, Fengqiang, Shao, Yang, Yang, Fengping, Liu, Ming, Huang, Jianhua, Zhu, Kai, Guo, Changcheng, Luo, Jun, Li, Wei, Yang, Bin, Shi, Jumei, Zheng, Junhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Termedia Publishing House 2013
Materias:	Basic Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648824/ https://www.ncbi.nlm.nih.gov/pubmed/23671445 http://dx.doi.org/10.5114/aoms.2013.34413

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