Cargando…

Endocytic Adaptor Protein Epsin Is Elevated in Prostate Cancer and Required for Cancer Progression

Epsins have an important role in mediating clathrin-mediated endocytosis of ubiquitinated cell surface receptors. The potential role for epsins in tumorigenesis and cancer metastasis by regulating intracellular signaling pathways has largely not been explored. Epsins are reportedly upregulated in se...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tessneer, Kandice L., Pasula, Satish, Cai, Xiaofeng, Dong, Yunzhou, Liu, Xiaolei, Yu, Lili, Hahn, Scott, McManus, John, Chen, Yiyuan, Chang, Baojun, Chen, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649151/ https://www.ncbi.nlm.nih.gov/pubmed/23691361 http://dx.doi.org/10.1155/2013/420597

Ejemplares similares

Epsin Family of Endocytic Adaptor Proteins as Oncogenic Regulators of Cancer Progression
por: Tessneer, Kandice L., et al.
Publicado: (2013)

Epsin is required for Dishevelled stability and Wnt signaling activation in colon cancer development
por: Chang, Baojun, et al.
Publicado: (2015)

Endocytic Adaptors in Cardiovascular Disease
por: Cui, Kui, et al.
Publicado: (2020)

Epsin deficiency impairs endocytosis by stalling the actin-dependent invagination of endocytic clathrin-coated pits
por: Messa, Mirko, et al.
Publicado: (2014)

Epsins Negatively Regulate Aortic Endothelial Cell Function by Augmenting Inflammatory Signaling
por: Dong, Yunzhou, et al.
Publicado: (2021)

GPCRs in Cancer: Protease-Activated Receptors, Endocytic Adaptors and Signaling
por: Arakaki, Aleena K. S., et al.
Publicado: (2018)

Cooperative regulation of endocytic vesicle transport by yeast Eps15-like protein Pan1p and epsins
por: Yoshida, Nao, et al.
Publicado: (2021)

Epsin-mediated degradation of IP3R1 fuels atherosclerosis
por: Dong, Yunzhou, et al.
Publicado: (2020)

Systemic lupus erythematosus variants modulate the function of an enhancer upstream of TNFAIP3
por: Pasula, Satish, et al.
Publicado: (2022)

A requirement for epsin in mitotic membrane and spindle organization
por: Liu, Zhonghua, et al.
Publicado: (2009)

Mimetic peptide of ubiquitin-interacting motif of epsin as a cancer therapeutic-perspective in brain tumor therapy through regulating VEGFR2 signaling
por: Dong, Yunzhou, et al.
Publicado: (2017)

Massively Parallel Reporter Assay Confirms Regulatory Potential of hQTLs and Reveals Important Variants in Lupus and Other Autoimmune Diseases
por: Fu, Yao, et al.
Publicado: (2023)

Endocytic Adaptor Protein Tollip Inhibits Canonical Wnt Signaling
por: Toruń, Anna, et al.
Publicado: (2015)

Arabidopsis clathrin adaptor EPSIN1 but not MODIFIED TRANSPORT TO THE VACOULE1 contributes to effective plant immunity against pathogenic Pseudomonas bacteria
por: Mason, Kelly, et al.
Publicado: (2023)

Stonin 2: An Adaptor-like Protein That Interacts with Components of the Endocytic Machinery
por: Martina, José A., et al.
Publicado: (2001)

Adapting for endocytosis: roles for endocytic sorting adaptors in directing neural development
por: Yap, Chan Choo, et al.
Publicado: (2015)

Safeguards of Neurotransmission: Endocytic Adaptors as Regulators of Synaptic Vesicle Composition and Function
por: Kaempf, Natalie, et al.
Publicado: (2017)

The protein kinase Akt acts as a coat adaptor in endocytic recycling
por: Hsu, Jia-Wei, et al.
Publicado: (2020)

PTPN23 binds the dynein adaptor BICD1 and is required for endocytic sorting of neurotrophin receptors
por: Budzinska, Marta I., et al.
Publicado: (2020)

Sorting it out: AP-2 and alternate clathrin adaptors in endocytic cargo selection
por: Traub, Linton M.
Publicado: (2003)

The Endocytic Adaptor Eps15 Controls Marginal Zone B Cell Numbers
por: Pozzi, Benedetta, et al.
Publicado: (2012)

Transcriptomic Analysis of Extracellular RNA Governed by the Endocytic Adaptor Protein Cin1 of Cryptococcus deneoformans
por: Liu, Muxing, et al.
Publicado: (2020)

Biomechanical Role of Epsin in Influenza A Virus Entry
por: Joseph, Jophin G., et al.
Publicado: (2022)

The adaptor protein p62/SQSTM1 in osteoclast signaling pathways
por: McManus, Stephen, et al.
Publicado: (2012)

Molecular basis of synaptic vesicle cargo recognition by the endocytic sorting adaptor stonin 2
por: Jung, Nadja, et al.
Publicado: (2007)

Correction: The Endocytic Adaptor Eps15 Controls Marginal Zone B Cell Numbers
por: Pozzi, Benedetta, et al.
Publicado: (2013)

Deficiency in the endocytic adaptor proteins PHETA1/2 impairs renal and craniofacial development
por: Ates, Kristin M., et al.
Publicado: (2020)

Endocytic Adaptor Proteins in Health and Disease: Lessons from Model Organisms and Human Mutations
por: Azarnia Tehran, Domenico, et al.
Publicado: (2019)

Contributions of epsinR and gadkin to clathrin-mediated intracellular trafficking
por: Hirst, Jennifer, et al.
Publicado: (2015)

Spatial Control of Epsin-induced Clathrin Assembly by Membrane Curvature
por: Holkar, Sachin S., et al.
Publicado: (2015)

Epsin and Sla2 form assemblies through phospholipid interfaces
por: Garcia-Alai, Maria M., et al.
Publicado: (2018)

Epsin 3 potentiates the NF-κB signaling pathway to regulate apoptosis in breast cancer
por: Wu, Qianxue, et al.
Publicado: (2022)

UIM domain-dependent recruitment of the endocytic adaptor protein Eps15 to ubiquitin-enriched endosomes
por: Gucwa, Azad L, et al.
Publicado: (2014)

CRACR2a is a calcium-activated dynein adaptor protein that regulates endocytic traffic
por: Wang, Yuxiao, et al.
Publicado: (2019)

SGIP1α functions as a selective endocytic adaptor for the internalization of synaptotagmin 1 at synapses
por: Lee, Sang-Eun, et al.
Publicado: (2019)

Lowe syndrome–linked endocytic adaptors direct membrane cycling kinetics with OCRL in Dictyostelium discoideum
por: Luscher, Alexandre, et al.
Publicado: (2019)

Membrane Binding and Self-Association of the Epsin N-Terminal Homology Domain
por: Lai, Chun-Liang, et al.
Publicado: (2012)

Single Particle Fluorescence Burst Analysis of Epsin Induced Membrane Fission
por: Brooks, Arielle, et al.
Publicado: (2015)

Epsin1 modulates synaptic vesicle retrieval capacity at CNS synapses
por: Kyung, Jae Won, et al.
Publicado: (2016)

Epsin15 Homology Domains: Role in the Pathogenesis of Pulmonary Arterial Hypertension
por: Predescu, Dan, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_k1qptevol29qgum7tmer3bmcol