Polyomavirus JC in the Context of Immunosuppression: A Series of Adaptive, DNA Replication-Driven Recombination Events in the Development of Progressive Multifocal Leukoencephalopathy

Polyomavirus JC (JCV) is the etiological agent of progressive multifocal leukoencephalopathy (PML), a demyelinating infection of oligodendrocytes in the brain. PML, a frequently fatal opportunistic infection in AIDS, has also emerged as a consequence of treatment with several new immunosuppressive t...

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Detalles Bibliográficos
Autores principales: Johnson, Edward M., Wortman, Margaret J., Dagdanova, Ayuna V., Lundberg, Patric S., Daniel, Dianne C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649189/
https://www.ncbi.nlm.nih.gov/pubmed/23690820
http://dx.doi.org/10.1155/2013/197807

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