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Saturated Fatty Acid-Induced Cytotoxicity in Liver Cells Does Not Involve Phosphatase and Tensin Homologue Deleted on Chromosome 10

Liver specific deletion of the tumor suppressor phosphatase and tensin homologue deleted on chromosome 10 (PTEN) induces steatosis and hypersensitivity to insulin. Saturated fatty acids, which induce endoplasmic reticulum stress and cell death, appear to increase PTEN, whereas unsaturated fatty acid...

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Detalles Bibliográficos
Autores principales:	Wang, Dong, Wei, Yuren, Frye, Melinda, Gentile, Christopher L., Pagliassotti, Michael J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649318/ https://www.ncbi.nlm.nih.gov/pubmed/23691291 http://dx.doi.org/10.1155/2013/514206

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