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Intestinal metastasis from primary epidermoid anal carcinoma in a 34 year old male presented with acute bowel obstruction

Squamous cell carcinoma (SCC) of the anal canal is a rare condition comprising only 2–4% of all cancers of the colon, rectum and anus. The most common sites of metastases are liver and lung. We report a case of 34-year-old male, who presented with diarrhoeal illness and an acutely tender protruding...

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Autores principales: Abdulmajed, M, Ghalib, A, Mohamed, M, Marsh, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JSCR Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649489/
https://www.ncbi.nlm.nih.gov/pubmed/24960777
http://dx.doi.org/10.1093/jscr/2012.2.1
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author Abdulmajed, M
Ghalib, A
Mohamed, M
Marsh, P
author_facet Abdulmajed, M
Ghalib, A
Mohamed, M
Marsh, P
author_sort Abdulmajed, M
collection PubMed
description Squamous cell carcinoma (SCC) of the anal canal is a rare condition comprising only 2–4% of all cancers of the colon, rectum and anus. The most common sites of metastases are liver and lung. We report a case of 34-year-old male, who presented with diarrhoeal illness and an acutely tender protruding anal lesion initially thought to be thrombosed external hemorrhoid. Examination under anaesthesia revealed a hard and fixed mass at the level of dentate line, which was biopsied. On histopathological examination, it was confirmed as primary moderately differentiated keratinising squamous cell carcinoma. Despite initial response to concomitant chemo-radiation, 4 months later, the patient presented with large bowel obstruction. On laparotomy, a large mass involving the terminal ileum and caecum was identified. Histopathological examination revealed metastatic spread from primary anal lesion. To the best of our knowledge, this is the first reported case of a squamous cell carcinoma of anus with bowel metastasis.
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spelling pubmed-36494892013-05-20 Intestinal metastasis from primary epidermoid anal carcinoma in a 34 year old male presented with acute bowel obstruction Abdulmajed, M Ghalib, A Mohamed, M Marsh, P J Surg Case Rep Colorectal Surgery Squamous cell carcinoma (SCC) of the anal canal is a rare condition comprising only 2–4% of all cancers of the colon, rectum and anus. The most common sites of metastases are liver and lung. We report a case of 34-year-old male, who presented with diarrhoeal illness and an acutely tender protruding anal lesion initially thought to be thrombosed external hemorrhoid. Examination under anaesthesia revealed a hard and fixed mass at the level of dentate line, which was biopsied. On histopathological examination, it was confirmed as primary moderately differentiated keratinising squamous cell carcinoma. Despite initial response to concomitant chemo-radiation, 4 months later, the patient presented with large bowel obstruction. On laparotomy, a large mass involving the terminal ileum and caecum was identified. Histopathological examination revealed metastatic spread from primary anal lesion. To the best of our knowledge, this is the first reported case of a squamous cell carcinoma of anus with bowel metastasis. JSCR Publishing Ltd 2012-02-01 /pmc/articles/PMC3649489/ /pubmed/24960777 http://dx.doi.org/10.1093/jscr/2012.2.1 Text en © JSCR
spellingShingle Colorectal Surgery
Abdulmajed, M
Ghalib, A
Mohamed, M
Marsh, P
Intestinal metastasis from primary epidermoid anal carcinoma in a 34 year old male presented with acute bowel obstruction
title Intestinal metastasis from primary epidermoid anal carcinoma in a 34 year old male presented with acute bowel obstruction
title_full Intestinal metastasis from primary epidermoid anal carcinoma in a 34 year old male presented with acute bowel obstruction
title_fullStr Intestinal metastasis from primary epidermoid anal carcinoma in a 34 year old male presented with acute bowel obstruction
title_full_unstemmed Intestinal metastasis from primary epidermoid anal carcinoma in a 34 year old male presented with acute bowel obstruction
title_short Intestinal metastasis from primary epidermoid anal carcinoma in a 34 year old male presented with acute bowel obstruction
title_sort intestinal metastasis from primary epidermoid anal carcinoma in a 34 year old male presented with acute bowel obstruction
topic Colorectal Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649489/
https://www.ncbi.nlm.nih.gov/pubmed/24960777
http://dx.doi.org/10.1093/jscr/2012.2.1
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AT mohamedm intestinalmetastasisfromprimaryepidermoidanalcarcinomaina34yearoldmalepresentedwithacutebowelobstruction
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