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Chordoma of the lumbar spine – a potential diagnosis not to be forgotten
Chordoma is a rare, malignant neoplasm thought to develop from the notochord. It most commonly occurs in the base of the cranium or the sacro-coccygeal region but around 15-20% affect the vertebral body. Extra-lesional resection with or without adjuvant radiotherapy is generally accepted as the main...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
JSCR Publishing Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649537/ https://www.ncbi.nlm.nih.gov/pubmed/24960132 http://dx.doi.org/10.1093/jscr/2012.5.4 |
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author | Breen, N Eames, N |
author_facet | Breen, N Eames, N |
author_sort | Breen, N |
collection | PubMed |
description | Chordoma is a rare, malignant neoplasm thought to develop from the notochord. It most commonly occurs in the base of the cranium or the sacro-coccygeal region but around 15-20% affect the vertebral body. Extra-lesional resection with or without adjuvant radiotherapy is generally accepted as the mainstay of treatment for this slow-growing tumour. We present a case whereby a patient with a solitary L3 vertebral body lesion causing caudal compression was treated with spinal decompression and posterior stabilisation. Pre-operative biopsy was not performed as the lesion was presumed to be a metastatic deposit from a co-existing renal mass. Intra-operative biopsy, however, identified the tumour to be chordoma of the L3 vertebral body which would have been more appropriately treated with ‘en-bloc’ excision. This case highlights the importance of pre-operative tissue diagnosis, and that, although rare (0.8 per 100,000), chordoma should always be considered. |
format | Online Article Text |
id | pubmed-3649537 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | JSCR Publishing Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-36495372013-05-20 Chordoma of the lumbar spine – a potential diagnosis not to be forgotten Breen, N Eames, N J Surg Case Rep Trauma & Orthopaedic Surgery Chordoma is a rare, malignant neoplasm thought to develop from the notochord. It most commonly occurs in the base of the cranium or the sacro-coccygeal region but around 15-20% affect the vertebral body. Extra-lesional resection with or without adjuvant radiotherapy is generally accepted as the mainstay of treatment for this slow-growing tumour. We present a case whereby a patient with a solitary L3 vertebral body lesion causing caudal compression was treated with spinal decompression and posterior stabilisation. Pre-operative biopsy was not performed as the lesion was presumed to be a metastatic deposit from a co-existing renal mass. Intra-operative biopsy, however, identified the tumour to be chordoma of the L3 vertebral body which would have been more appropriately treated with ‘en-bloc’ excision. This case highlights the importance of pre-operative tissue diagnosis, and that, although rare (0.8 per 100,000), chordoma should always be considered. JSCR Publishing Ltd 2012-05-01 /pmc/articles/PMC3649537/ /pubmed/24960132 http://dx.doi.org/10.1093/jscr/2012.5.4 Text en © JSCR |
spellingShingle | Trauma & Orthopaedic Surgery Breen, N Eames, N Chordoma of the lumbar spine – a potential diagnosis not to be forgotten |
title | Chordoma of the lumbar spine – a potential diagnosis not to be forgotten |
title_full | Chordoma of the lumbar spine – a potential diagnosis not to be forgotten |
title_fullStr | Chordoma of the lumbar spine – a potential diagnosis not to be forgotten |
title_full_unstemmed | Chordoma of the lumbar spine – a potential diagnosis not to be forgotten |
title_short | Chordoma of the lumbar spine – a potential diagnosis not to be forgotten |
title_sort | chordoma of the lumbar spine – a potential diagnosis not to be forgotten |
topic | Trauma & Orthopaedic Surgery |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649537/ https://www.ncbi.nlm.nih.gov/pubmed/24960132 http://dx.doi.org/10.1093/jscr/2012.5.4 |
work_keys_str_mv | AT breenn chordomaofthelumbarspineapotentialdiagnosisnottobeforgotten AT eamesn chordomaofthelumbarspineapotentialdiagnosisnottobeforgotten |