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A Review of Pterostilbene Antioxidant Activity and Disease Modification

Pterostilbene (trans-3,5-dimethoxy-4-hydroxystilbene) is a natural dietary compound and the primary antioxidant component of blueberries. It has increased bioavailability in comparison to other stilbene compounds, which may enhance its dietary benefit and possibly contribute to a valuable clinical e...

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Detalles Bibliográficos
Autores principales: McCormack, Denise, McFadden, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649683/
https://www.ncbi.nlm.nih.gov/pubmed/23691264
http://dx.doi.org/10.1155/2013/575482
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author McCormack, Denise
McFadden, David
author_facet McCormack, Denise
McFadden, David
author_sort McCormack, Denise
collection PubMed
description Pterostilbene (trans-3,5-dimethoxy-4-hydroxystilbene) is a natural dietary compound and the primary antioxidant component of blueberries. It has increased bioavailability in comparison to other stilbene compounds, which may enhance its dietary benefit and possibly contribute to a valuable clinical effect. Multiple studies have demonstrated the antioxidant activity of pterostilbene in both in vitro and in vivo models illustrating both preventative and therapeutic benefits. The antioxidant activity of pterostilbene has been implicated in anticarcinogenesis, modulation of neurological disease, anti-inflammation, attenuation of vascular disease, and amelioration of diabetes. In this review, we explore the antioxidant properties of pterostilbene and its relationship to common disease pathways and give a summary of the clinical potential of pterostilbene in the prevention and treatment of various medical conditions.
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spelling pubmed-36496832013-05-20 A Review of Pterostilbene Antioxidant Activity and Disease Modification McCormack, Denise McFadden, David Oxid Med Cell Longev Review Article Pterostilbene (trans-3,5-dimethoxy-4-hydroxystilbene) is a natural dietary compound and the primary antioxidant component of blueberries. It has increased bioavailability in comparison to other stilbene compounds, which may enhance its dietary benefit and possibly contribute to a valuable clinical effect. Multiple studies have demonstrated the antioxidant activity of pterostilbene in both in vitro and in vivo models illustrating both preventative and therapeutic benefits. The antioxidant activity of pterostilbene has been implicated in anticarcinogenesis, modulation of neurological disease, anti-inflammation, attenuation of vascular disease, and amelioration of diabetes. In this review, we explore the antioxidant properties of pterostilbene and its relationship to common disease pathways and give a summary of the clinical potential of pterostilbene in the prevention and treatment of various medical conditions. Hindawi Publishing Corporation 2013 2013-04-04 /pmc/articles/PMC3649683/ /pubmed/23691264 http://dx.doi.org/10.1155/2013/575482 Text en Copyright © 2013 D. McCormack and D. McFadden. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
McCormack, Denise
McFadden, David
A Review of Pterostilbene Antioxidant Activity and Disease Modification
title A Review of Pterostilbene Antioxidant Activity and Disease Modification
title_full A Review of Pterostilbene Antioxidant Activity and Disease Modification
title_fullStr A Review of Pterostilbene Antioxidant Activity and Disease Modification
title_full_unstemmed A Review of Pterostilbene Antioxidant Activity and Disease Modification
title_short A Review of Pterostilbene Antioxidant Activity and Disease Modification
title_sort review of pterostilbene antioxidant activity and disease modification
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649683/
https://www.ncbi.nlm.nih.gov/pubmed/23691264
http://dx.doi.org/10.1155/2013/575482
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