Reducing Haemorrhagic Transformation after Thrombolysis for Stroke: A Strategy Utilising Minocycline

Haemorrhagic transformation (HT) of recently ischaemic brain is a feared complication of thrombolytic therapy that may be caused or compounded by ischaemia-induced activation of matrix metalloproteinases (MMPs). The tetracycline antibiotic minocycline inhibits matrix MMPs and reduces macroscopic HT...

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Detalles Bibliográficos
Autores principales: Blacker, David J., Prentice, David, Alvaro, Anthony, Bates, Timothy R., Bynevelt, Michael, Kelly, Andrew, Kho, Lay Kun, Kohler, Edith, Hankey, Graeme J., Thompson, Andrew, Major, Taryn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649751/
https://www.ncbi.nlm.nih.gov/pubmed/23691430
http://dx.doi.org/10.1155/2013/362961

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