From Mouse to Human: Evolutionary Genomics Analysis of Human Orthologs of Essential Genes

Understanding the core set of genes that are necessary for basic developmental functions is one of the central goals in biology. Studies in model organisms identified a significant fraction of essential genes through the analysis of null-mutations that lead to lethality. Recent large-scale next-gene...

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Detalles Bibliográficos
Autores principales: Georgi, Benjamin, Voight, Benjamin F., Bućan, Maja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649967/
https://www.ncbi.nlm.nih.gov/pubmed/23675308
http://dx.doi.org/10.1371/journal.pgen.1003484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649967/
https://www.ncbi.nlm.nih.gov/pubmed/23675308
http://dx.doi.org/10.1371/journal.pgen.1003484

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