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From Mouse to Human: Evolutionary Genomics Analysis of Human Orthologs of Essential Genes
Understanding the core set of genes that are necessary for basic developmental functions is one of the central goals in biology. Studies in model organisms identified a significant fraction of essential genes through the analysis of null-mutations that lead to lethality. Recent large-scale next-gene...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649967/ https://www.ncbi.nlm.nih.gov/pubmed/23675308 http://dx.doi.org/10.1371/journal.pgen.1003484 |