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Coordinated Regulation of Chromatophore Differentiation and Melanogenesis during the Ontogeny of Skin Pigmentation of Solea senegalensis (Kaup, 1858)

Abnormal pigmentation of Senegalese sole has been described as one problem facing the full exploitation of its commercial production. To improve our understanding of flatfish pigmentation of this commercially important species we have evaluated eleven genes related to two different processes of pigm...

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Autores principales: Darias, Maria J., Andree, Karl B., Boglino, Anaïs, Fernández, Ignacio, Estévez, Alicia, Gisbert, Enric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650040/
https://www.ncbi.nlm.nih.gov/pubmed/23671650
http://dx.doi.org/10.1371/journal.pone.0063005
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author Darias, Maria J.
Andree, Karl B.
Boglino, Anaïs
Fernández, Ignacio
Estévez, Alicia
Gisbert, Enric
author_facet Darias, Maria J.
Andree, Karl B.
Boglino, Anaïs
Fernández, Ignacio
Estévez, Alicia
Gisbert, Enric
author_sort Darias, Maria J.
collection PubMed
description Abnormal pigmentation of Senegalese sole has been described as one problem facing the full exploitation of its commercial production. To improve our understanding of flatfish pigmentation of this commercially important species we have evaluated eleven genes related to two different processes of pigmentation: melanophore differentiation, and melanin production. The temporal distribution of gene expression peaks corresponds well with changes in pigmentation patterns and the intensity of skin melanization. Several gene ratios were also examined to put in perspective possible genetic markers for the different stages of normal pigmentation development. Further, the phenotypic changes that occur during morphogenesis correspond well with the main transitions in gene expression that occur. Given the dramatic phenotypic alterations which flatfish undergo, including the asymmetric coloration that occurs between the ocular and the blind side, and the synchrony of the two processes of morphogenesis and pigmentation ontogenesis, these species constitute an interesting model for the study of pigmentation. In this study we present a first approximation towards explaining the genetic mechanisms for regulating pigmentation ontogeny in Senegalese sole, Solea senegalensis.
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spelling pubmed-36500402013-05-13 Coordinated Regulation of Chromatophore Differentiation and Melanogenesis during the Ontogeny of Skin Pigmentation of Solea senegalensis (Kaup, 1858) Darias, Maria J. Andree, Karl B. Boglino, Anaïs Fernández, Ignacio Estévez, Alicia Gisbert, Enric PLoS One Research Article Abnormal pigmentation of Senegalese sole has been described as one problem facing the full exploitation of its commercial production. To improve our understanding of flatfish pigmentation of this commercially important species we have evaluated eleven genes related to two different processes of pigmentation: melanophore differentiation, and melanin production. The temporal distribution of gene expression peaks corresponds well with changes in pigmentation patterns and the intensity of skin melanization. Several gene ratios were also examined to put in perspective possible genetic markers for the different stages of normal pigmentation development. Further, the phenotypic changes that occur during morphogenesis correspond well with the main transitions in gene expression that occur. Given the dramatic phenotypic alterations which flatfish undergo, including the asymmetric coloration that occurs between the ocular and the blind side, and the synchrony of the two processes of morphogenesis and pigmentation ontogenesis, these species constitute an interesting model for the study of pigmentation. In this study we present a first approximation towards explaining the genetic mechanisms for regulating pigmentation ontogeny in Senegalese sole, Solea senegalensis. Public Library of Science 2013-05-09 /pmc/articles/PMC3650040/ /pubmed/23671650 http://dx.doi.org/10.1371/journal.pone.0063005 Text en © 2013 Darias et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Darias, Maria J.
Andree, Karl B.
Boglino, Anaïs
Fernández, Ignacio
Estévez, Alicia
Gisbert, Enric
Coordinated Regulation of Chromatophore Differentiation and Melanogenesis during the Ontogeny of Skin Pigmentation of Solea senegalensis (Kaup, 1858)
title Coordinated Regulation of Chromatophore Differentiation and Melanogenesis during the Ontogeny of Skin Pigmentation of Solea senegalensis (Kaup, 1858)
title_full Coordinated Regulation of Chromatophore Differentiation and Melanogenesis during the Ontogeny of Skin Pigmentation of Solea senegalensis (Kaup, 1858)
title_fullStr Coordinated Regulation of Chromatophore Differentiation and Melanogenesis during the Ontogeny of Skin Pigmentation of Solea senegalensis (Kaup, 1858)
title_full_unstemmed Coordinated Regulation of Chromatophore Differentiation and Melanogenesis during the Ontogeny of Skin Pigmentation of Solea senegalensis (Kaup, 1858)
title_short Coordinated Regulation of Chromatophore Differentiation and Melanogenesis during the Ontogeny of Skin Pigmentation of Solea senegalensis (Kaup, 1858)
title_sort coordinated regulation of chromatophore differentiation and melanogenesis during the ontogeny of skin pigmentation of solea senegalensis (kaup, 1858)
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650040/
https://www.ncbi.nlm.nih.gov/pubmed/23671650
http://dx.doi.org/10.1371/journal.pone.0063005
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