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CLCAs - A Family of Metalloproteases of Intriguing Phylogenetic Distribution and with Cases of Substituted Catalytic Sites

The zinc-dependent metalloproteases with His-Glu-x-x-His (HExxH) active site motif, zincins, are a broad group of proteins involved in many metabolic and regulatory functions, and found in all forms of life. Human genome contains more than 100 genes encoding proteins with known zincin-like domains....

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Detalles Bibliográficos
Autores principales: Lenart, Anna, Dudkiewicz, Małgorzata, Grynberg, Marcin, Pawłowski, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650047/
https://www.ncbi.nlm.nih.gov/pubmed/23671590
http://dx.doi.org/10.1371/journal.pone.0062272