Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis

Intestinal microbiota metabolism of choline/phosphatidylcholine produces trimethylamine (TMA), which is further metabolized to a proatherogenic species, trimethylamine-N-oxide (TMAO). Herein we demonstrate that intestinal microbiota metabolism of dietary L-carnitine, a trimethylamine abundant in red...

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Detalles Bibliográficos
Autores principales: Koeth, Robert A., Wang, Zeneng, Levison, Bruce S., Buffa, Jennifer A., Org, Elin, Sheehy, Brendan T., Britt, Earl B., Fu, Xiaoming, Wu, Yuping, Li, Lin, Smith, Jonathan D., DiDonato, Joseph A., Chen, Jun, Li, Hongzhe, Wu, Gary D., Lewis, James D., Warrier, Manya, Brown, J. Mark, Krauss, Ronald M., Tang, W. H. Wilson, Bushman, Frederic D., Lusis, Aldons J., Hazen, Stanley L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650111/
https://www.ncbi.nlm.nih.gov/pubmed/23563705
http://dx.doi.org/10.1038/nm.3145

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