Therapeutic Delivery of MicroRNA-29b by Cationic Lipoplexes for Lung Cancer

MicroRNA-29b (miR-29b) expression has been shown to be reduced in non-small–cell lung cancer (NSCLC) tissues. Here, we have identified the oncogene cyclin-dependent protein kinase 6 (CDK6) as a direct target of miR-29b in lung cancer. We hypothesized that in vivo restoration of miR-29b and thus targ...

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Detalles Bibliográficos
Autores principales: Wu, Yun, Crawford, Melissa, Mao, Yicheng, Lee, Robert J, Davis, Ian C, Elton, Terry S, Lee, L James, Nana-Sinkam, Serge P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650246/
https://www.ncbi.nlm.nih.gov/pubmed/23591808
http://dx.doi.org/10.1038/mtna.2013.14

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