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RANGE: Gene Transfer of Reversibly Controlled Polycistronic Genes

We developed a single vector recombinant adeno-associated viral (rAAV) expression system for spatial and reversible control of polycistronic gene expression. Our approach (i) integrates the advantages of the tetracycline (Tet)-controlled transcriptional silencer tTS(Kid) and the self-cleaving 2A pep...

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Detalles Bibliográficos
Autores principales:	Chen, Yiwei, Cao, Liji, Luo, Chonglin, Ditzel, Désirée AW, Peter, Jörg, Sprengel, Rolf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Methods - Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650247/ https://www.ncbi.nlm.nih.gov/pubmed/23571608 http://dx.doi.org/10.1038/mtna.2013.15

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