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A SILAC-based Approach Identifies Substrates of Caspase-dependent Cleavage upon TRAIL-induced Apoptosis

The extracellular ligand-induced extrinsic pathway of apoptosis is executed via caspase protease cascades that activate downstream effectors by means of site-directed proteolysis. Here we identify proteome changes upon the induction of apoptosis by the cytokine tumor necrosis factor–related apoptosi...

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Detalles Bibliográficos
Autores principales:	Stoehr, Gabriele, Schaab, Christoph, Graumann, Johannes, Mann, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Biochemistry and Molecular Biology 2013
Materias:	Technological Innovation and Resources
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650350/ https://www.ncbi.nlm.nih.gov/pubmed/23319142 http://dx.doi.org/10.1074/mcp.M112.024679

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