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Molecular Determinants of Regulatory T Cell Development: The Essential Roles of Epigenetic Changes

Regulatory T (Treg) cells constitute a distinct T cell subset, which plays a key role in immune tolerance and homeostasis. The transcription factor Foxp3 controls a substantial part of Treg cell development and function. Yet its expression alone is insufficient for conferring developmental and funct...

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Detalles Bibliográficos
Autores principales:	Kitagawa, Yohko, Ohkura, Naganari, Sakaguchi, Shimon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650462/ https://www.ncbi.nlm.nih.gov/pubmed/23675373 http://dx.doi.org/10.3389/fimmu.2013.00106

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