The impact of JNK inhibitor D-JNKI-1 in a murine model of chronic colitis induced by dextran sulfate sodium

PURPOSE: The c-Jun N-terminal kinases (JNK) are involved in the activation of T cells and the synthesis of proinflammatory cytokines. Several studies have established the relevance of the JNK pathway in inflammatory bowel diseases. The present study analyzed the therapeutic effect of D-JNKI-1, a spe...

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Detalles Bibliográficos
Autores principales: Kersting, Sabine, Behrendt, Volker, Kersting, Jonas, Reinecke, Kirstin, Hilgert, Christoph, Stricker, Ingo, Herdegen, Thomas, Janot, Monika S, Uhl, Waldemar, Chromik, Ansgar M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650567/
https://www.ncbi.nlm.nih.gov/pubmed/23667316
http://dx.doi.org/10.2147/JIR.S40092

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