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Broca's area and its striatal and thalamic connections: a diffusion-MRI tractography study
In the recent decades structural connectivity between Broca's area and the basal ganglia has been postulated in the literature, though no direct evidence of this connectivity has yet been presented. The current study investigates this connectivity using a novel diffusion-weighted imaging (DWI)...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650618/ https://www.ncbi.nlm.nih.gov/pubmed/23675324 http://dx.doi.org/10.3389/fnana.2013.00008 |
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author | Ford, Anastasia A. Triplett, William Sudhyadhom, Atchar Gullett, Joseph McGregor, Keith FitzGerald, David B. Mareci, Thomas White, Keith Crosson, Bruce |
author_facet | Ford, Anastasia A. Triplett, William Sudhyadhom, Atchar Gullett, Joseph McGregor, Keith FitzGerald, David B. Mareci, Thomas White, Keith Crosson, Bruce |
author_sort | Ford, Anastasia A. |
collection | PubMed |
description | In the recent decades structural connectivity between Broca's area and the basal ganglia has been postulated in the literature, though no direct evidence of this connectivity has yet been presented. The current study investigates this connectivity using a novel diffusion-weighted imaging (DWI) fiber tracking method in humans in vivo. Our findings suggest direct connections between sub-regions of Broca's area and the anterior one-third of the putamen, as well as the ventral anterior nucleus of the thalamus. Thus, we are the first to provide a detailed account of inferred circuitry involving basal ganglia, thalamus, and Broca's area, which would be a prerequisite to substantiate their support of language processing. |
format | Online Article Text |
id | pubmed-3650618 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-36506182013-05-14 Broca's area and its striatal and thalamic connections: a diffusion-MRI tractography study Ford, Anastasia A. Triplett, William Sudhyadhom, Atchar Gullett, Joseph McGregor, Keith FitzGerald, David B. Mareci, Thomas White, Keith Crosson, Bruce Front Neuroanat Neuroscience In the recent decades structural connectivity between Broca's area and the basal ganglia has been postulated in the literature, though no direct evidence of this connectivity has yet been presented. The current study investigates this connectivity using a novel diffusion-weighted imaging (DWI) fiber tracking method in humans in vivo. Our findings suggest direct connections between sub-regions of Broca's area and the anterior one-third of the putamen, as well as the ventral anterior nucleus of the thalamus. Thus, we are the first to provide a detailed account of inferred circuitry involving basal ganglia, thalamus, and Broca's area, which would be a prerequisite to substantiate their support of language processing. Frontiers Media S.A. 2013-05-10 /pmc/articles/PMC3650618/ /pubmed/23675324 http://dx.doi.org/10.3389/fnana.2013.00008 Text en Copyright © 2013 Ford, Triplett, Sudhyadhom, Gullett, McGregor, FitzGerald, Mareci, White and Crosson. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc. |
spellingShingle | Neuroscience Ford, Anastasia A. Triplett, William Sudhyadhom, Atchar Gullett, Joseph McGregor, Keith FitzGerald, David B. Mareci, Thomas White, Keith Crosson, Bruce Broca's area and its striatal and thalamic connections: a diffusion-MRI tractography study |
title | Broca's area and its striatal and thalamic connections: a diffusion-MRI tractography study |
title_full | Broca's area and its striatal and thalamic connections: a diffusion-MRI tractography study |
title_fullStr | Broca's area and its striatal and thalamic connections: a diffusion-MRI tractography study |
title_full_unstemmed | Broca's area and its striatal and thalamic connections: a diffusion-MRI tractography study |
title_short | Broca's area and its striatal and thalamic connections: a diffusion-MRI tractography study |
title_sort | broca's area and its striatal and thalamic connections: a diffusion-mri tractography study |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650618/ https://www.ncbi.nlm.nih.gov/pubmed/23675324 http://dx.doi.org/10.3389/fnana.2013.00008 |
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