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Broca's area and its striatal and thalamic connections: a diffusion-MRI tractography study

In the recent decades structural connectivity between Broca's area and the basal ganglia has been postulated in the literature, though no direct evidence of this connectivity has yet been presented. The current study investigates this connectivity using a novel diffusion-weighted imaging (DWI)...

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Autores principales: Ford, Anastasia A., Triplett, William, Sudhyadhom, Atchar, Gullett, Joseph, McGregor, Keith, FitzGerald, David B., Mareci, Thomas, White, Keith, Crosson, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650618/
https://www.ncbi.nlm.nih.gov/pubmed/23675324
http://dx.doi.org/10.3389/fnana.2013.00008
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author Ford, Anastasia A.
Triplett, William
Sudhyadhom, Atchar
Gullett, Joseph
McGregor, Keith
FitzGerald, David B.
Mareci, Thomas
White, Keith
Crosson, Bruce
author_facet Ford, Anastasia A.
Triplett, William
Sudhyadhom, Atchar
Gullett, Joseph
McGregor, Keith
FitzGerald, David B.
Mareci, Thomas
White, Keith
Crosson, Bruce
author_sort Ford, Anastasia A.
collection PubMed
description In the recent decades structural connectivity between Broca's area and the basal ganglia has been postulated in the literature, though no direct evidence of this connectivity has yet been presented. The current study investigates this connectivity using a novel diffusion-weighted imaging (DWI) fiber tracking method in humans in vivo. Our findings suggest direct connections between sub-regions of Broca's area and the anterior one-third of the putamen, as well as the ventral anterior nucleus of the thalamus. Thus, we are the first to provide a detailed account of inferred circuitry involving basal ganglia, thalamus, and Broca's area, which would be a prerequisite to substantiate their support of language processing.
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spelling pubmed-36506182013-05-14 Broca's area and its striatal and thalamic connections: a diffusion-MRI tractography study Ford, Anastasia A. Triplett, William Sudhyadhom, Atchar Gullett, Joseph McGregor, Keith FitzGerald, David B. Mareci, Thomas White, Keith Crosson, Bruce Front Neuroanat Neuroscience In the recent decades structural connectivity between Broca's area and the basal ganglia has been postulated in the literature, though no direct evidence of this connectivity has yet been presented. The current study investigates this connectivity using a novel diffusion-weighted imaging (DWI) fiber tracking method in humans in vivo. Our findings suggest direct connections between sub-regions of Broca's area and the anterior one-third of the putamen, as well as the ventral anterior nucleus of the thalamus. Thus, we are the first to provide a detailed account of inferred circuitry involving basal ganglia, thalamus, and Broca's area, which would be a prerequisite to substantiate their support of language processing. Frontiers Media S.A. 2013-05-10 /pmc/articles/PMC3650618/ /pubmed/23675324 http://dx.doi.org/10.3389/fnana.2013.00008 Text en Copyright © 2013 Ford, Triplett, Sudhyadhom, Gullett, McGregor, FitzGerald, Mareci, White and Crosson. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.
spellingShingle Neuroscience
Ford, Anastasia A.
Triplett, William
Sudhyadhom, Atchar
Gullett, Joseph
McGregor, Keith
FitzGerald, David B.
Mareci, Thomas
White, Keith
Crosson, Bruce
Broca's area and its striatal and thalamic connections: a diffusion-MRI tractography study
title Broca's area and its striatal and thalamic connections: a diffusion-MRI tractography study
title_full Broca's area and its striatal and thalamic connections: a diffusion-MRI tractography study
title_fullStr Broca's area and its striatal and thalamic connections: a diffusion-MRI tractography study
title_full_unstemmed Broca's area and its striatal and thalamic connections: a diffusion-MRI tractography study
title_short Broca's area and its striatal and thalamic connections: a diffusion-MRI tractography study
title_sort broca's area and its striatal and thalamic connections: a diffusion-mri tractography study
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650618/
https://www.ncbi.nlm.nih.gov/pubmed/23675324
http://dx.doi.org/10.3389/fnana.2013.00008
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