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Pediatric Asthma Mortality and Hospitalization Trends Across Asia Pacific Relationship With Asthma Drug Utilization Patterns
BACKGROUND: The wide variability in prevalence of childhood asthma across Asia Pacific is well documented, but less is known about its trends in mortality and hospitalization. OBJECTIVES: To examine pediatric asthma mortality and hospitalization trends of selected countries across Asia Pacific, and...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
World Allergy Organization
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651014/ https://www.ncbi.nlm.nih.gov/pubmed/23283014 http://dx.doi.org/10.1097/WOX.0b013e3181a7c288 |
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author | Chua, Kun Lin Soh, Shu E Ma, Stefan Lee, Bee Wah |
author_facet | Chua, Kun Lin Soh, Shu E Ma, Stefan Lee, Bee Wah |
author_sort | Chua, Kun Lin |
collection | PubMed |
description | BACKGROUND: The wide variability in prevalence of childhood asthma across Asia Pacific is well documented, but less is known about its trends in mortality and hospitalization. OBJECTIVES: To examine pediatric asthma mortality and hospitalization trends of selected countries across Asia Pacific, and also patterns of asthma drug utilization. MATERIALS AND METHODS: Mortality and population data were sourced from the World Health Organization's mortality database. Data on hospitalization were obtained by direct inquiry and from government and scientific publications. Drug use for asthma was expressed as a controller-to-reliever (C:R) ratio (ie, units of inhaled corticosteroids/units of short-acting β-agonists, sold in each country). Time-series regression analyses were used to examine temporal patterns and study association between deaths, hospitalizations, and drug use. RESULTS: Japan showed a decreasing trend in pediatric asthma mortality whereas an increase was observed in Thailand. Hospitalizations decreased in Australia and Singapore but increased in Taiwan, Republic of China. C:R ratios increased significantly across the countries. CONCLUSIONS: Mixed trends in pediatric asthma mortality and hospitalization rates were observed, which coincided with a uniform increase in C:R ratios. This may reflect importance of other aspects of asthma management besides pharmacotherapy. |
format | Online Article Text |
id | pubmed-3651014 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | World Allergy Organization |
record_format | MEDLINE/PubMed |
spelling | pubmed-36510142013-07-12 Pediatric Asthma Mortality and Hospitalization Trends Across Asia Pacific Relationship With Asthma Drug Utilization Patterns Chua, Kun Lin Soh, Shu E Ma, Stefan Lee, Bee Wah World Allergy Organ J Original Research BACKGROUND: The wide variability in prevalence of childhood asthma across Asia Pacific is well documented, but less is known about its trends in mortality and hospitalization. OBJECTIVES: To examine pediatric asthma mortality and hospitalization trends of selected countries across Asia Pacific, and also patterns of asthma drug utilization. MATERIALS AND METHODS: Mortality and population data were sourced from the World Health Organization's mortality database. Data on hospitalization were obtained by direct inquiry and from government and scientific publications. Drug use for asthma was expressed as a controller-to-reliever (C:R) ratio (ie, units of inhaled corticosteroids/units of short-acting β-agonists, sold in each country). Time-series regression analyses were used to examine temporal patterns and study association between deaths, hospitalizations, and drug use. RESULTS: Japan showed a decreasing trend in pediatric asthma mortality whereas an increase was observed in Thailand. Hospitalizations decreased in Australia and Singapore but increased in Taiwan, Republic of China. C:R ratios increased significantly across the countries. CONCLUSIONS: Mixed trends in pediatric asthma mortality and hospitalization rates were observed, which coincided with a uniform increase in C:R ratios. This may reflect importance of other aspects of asthma management besides pharmacotherapy. World Allergy Organization 2009-05-15 /pmc/articles/PMC3651014/ /pubmed/23283014 http://dx.doi.org/10.1097/WOX.0b013e3181a7c288 Text en Copyright ©2009 World Allergy Organization; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Research Chua, Kun Lin Soh, Shu E Ma, Stefan Lee, Bee Wah Pediatric Asthma Mortality and Hospitalization Trends Across Asia Pacific Relationship With Asthma Drug Utilization Patterns |
title | Pediatric Asthma Mortality and Hospitalization Trends Across Asia Pacific Relationship With Asthma Drug Utilization Patterns |
title_full | Pediatric Asthma Mortality and Hospitalization Trends Across Asia Pacific Relationship With Asthma Drug Utilization Patterns |
title_fullStr | Pediatric Asthma Mortality and Hospitalization Trends Across Asia Pacific Relationship With Asthma Drug Utilization Patterns |
title_full_unstemmed | Pediatric Asthma Mortality and Hospitalization Trends Across Asia Pacific Relationship With Asthma Drug Utilization Patterns |
title_short | Pediatric Asthma Mortality and Hospitalization Trends Across Asia Pacific Relationship With Asthma Drug Utilization Patterns |
title_sort | pediatric asthma mortality and hospitalization trends across asia pacific relationship with asthma drug utilization patterns |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651014/ https://www.ncbi.nlm.nih.gov/pubmed/23283014 http://dx.doi.org/10.1097/WOX.0b013e3181a7c288 |
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