A Rare Coexistence: Drug Induced Hepatitis and Meningitis in Association With Ibuprofen

Ibuprofen, a commonly used NSAID is reported to be associated with drug induced liver injury. Ibuprofen is also known to be associated with drug-induced meningitis especially in patients with connective tissue disorders. However presentation of hepatitis and meningitis in association with Ibuprofen...

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Autores principales: Nayudu, Suresh Kumar, Kavuturu, Shilpa, Niazi, Masooma, Daniel, Myrta, Dev, Anil, Kumbum, Kavitha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651076/
https://www.ncbi.nlm.nih.gov/pubmed/23671551
http://dx.doi.org/10.4021/jocmr1280w
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author Nayudu, Suresh Kumar
Kavuturu, Shilpa
Niazi, Masooma
Daniel, Myrta
Dev, Anil
Kumbum, Kavitha
author_facet Nayudu, Suresh Kumar
Kavuturu, Shilpa
Niazi, Masooma
Daniel, Myrta
Dev, Anil
Kumbum, Kavitha
author_sort Nayudu, Suresh Kumar
collection PubMed
description Ibuprofen, a commonly used NSAID is reported to be associated with drug induced liver injury. Ibuprofen is also known to be associated with drug-induced meningitis especially in patients with connective tissue disorders. However presentation of hepatitis and meningitis in association with Ibuprofen use in the same individual has never been reported. We present a case of young woman who developed abnormal liver chemistries and neurological symptoms while on Ibuprofen. Her liver biopsy findings were suggestive of drug induced liver injury and cerebrospinal fluid analysis was suggestive of aseptic meningitis. Clinical and biochemical improvement was noted on cessation of Ibuprofen.
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spelling pubmed-36510762013-05-13 A Rare Coexistence: Drug Induced Hepatitis and Meningitis in Association With Ibuprofen Nayudu, Suresh Kumar Kavuturu, Shilpa Niazi, Masooma Daniel, Myrta Dev, Anil Kumbum, Kavitha J Clin Med Res Case Report Ibuprofen, a commonly used NSAID is reported to be associated with drug induced liver injury. Ibuprofen is also known to be associated with drug-induced meningitis especially in patients with connective tissue disorders. However presentation of hepatitis and meningitis in association with Ibuprofen use in the same individual has never been reported. We present a case of young woman who developed abnormal liver chemistries and neurological symptoms while on Ibuprofen. Her liver biopsy findings were suggestive of drug induced liver injury and cerebrospinal fluid analysis was suggestive of aseptic meningitis. Clinical and biochemical improvement was noted on cessation of Ibuprofen. Elmer Press 2013-06 2013-04-23 /pmc/articles/PMC3651076/ /pubmed/23671551 http://dx.doi.org/10.4021/jocmr1280w Text en Copyright 2013, Nayudu et al. http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Nayudu, Suresh Kumar
Kavuturu, Shilpa
Niazi, Masooma
Daniel, Myrta
Dev, Anil
Kumbum, Kavitha
A Rare Coexistence: Drug Induced Hepatitis and Meningitis in Association With Ibuprofen
title A Rare Coexistence: Drug Induced Hepatitis and Meningitis in Association With Ibuprofen
title_full A Rare Coexistence: Drug Induced Hepatitis and Meningitis in Association With Ibuprofen
title_fullStr A Rare Coexistence: Drug Induced Hepatitis and Meningitis in Association With Ibuprofen
title_full_unstemmed A Rare Coexistence: Drug Induced Hepatitis and Meningitis in Association With Ibuprofen
title_short A Rare Coexistence: Drug Induced Hepatitis and Meningitis in Association With Ibuprofen
title_sort rare coexistence: drug induced hepatitis and meningitis in association with ibuprofen
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651076/
https://www.ncbi.nlm.nih.gov/pubmed/23671551
http://dx.doi.org/10.4021/jocmr1280w
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