Cargando…
Staphylococcus aureus and Chronic Airway Disease
Staphylococcus aureus (S. aureus) is correlated with the development of persistent severe inflammatory disease of the upper airway including chronic rhinosinusitis with nasal polyps. This inflammation of the upper airways is characterized by a T-helper 2-driven disease: interleukin-5 is significantl...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
World Allergy Organization
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651149/ https://www.ncbi.nlm.nih.gov/pubmed/23282714 http://dx.doi.org/10.1097/WOX.0b013e3181ecd8ae |
_version_ | 1782269173064269824 |
---|---|
author | Derycke, Lara Pérez-Novo, Claudina Van Crombruggen, Koen Corriveau, Marie-Noëlle Bachert, Claus |
author_facet | Derycke, Lara Pérez-Novo, Claudina Van Crombruggen, Koen Corriveau, Marie-Noëlle Bachert, Claus |
author_sort | Derycke, Lara |
collection | PubMed |
description | Staphylococcus aureus (S. aureus) is correlated with the development of persistent severe inflammatory disease of the upper airway including chronic rhinosinusitis with nasal polyps. This inflammation of the upper airways is characterized by a T-helper 2-driven disease: interleukin-5 is significantly increased and local production of immunoglobulin E is observed. S. aureus and its enterotoxins are deregulating the tissue inflammation at different levels: structural cells and the innate and adaptive immune system. Knowing the triggers of the pathomechanisms involved will greatly help us to find new therapeutic approaches to resolve this chronic inflammatory process. |
format | Online Article Text |
id | pubmed-3651149 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | World Allergy Organization |
record_format | MEDLINE/PubMed |
spelling | pubmed-36511492013-07-12 Staphylococcus aureus and Chronic Airway Disease Derycke, Lara Pérez-Novo, Claudina Van Crombruggen, Koen Corriveau, Marie-Noëlle Bachert, Claus World Allergy Organ J Invited Review Staphylococcus aureus (S. aureus) is correlated with the development of persistent severe inflammatory disease of the upper airway including chronic rhinosinusitis with nasal polyps. This inflammation of the upper airways is characterized by a T-helper 2-driven disease: interleukin-5 is significantly increased and local production of immunoglobulin E is observed. S. aureus and its enterotoxins are deregulating the tissue inflammation at different levels: structural cells and the innate and adaptive immune system. Knowing the triggers of the pathomechanisms involved will greatly help us to find new therapeutic approaches to resolve this chronic inflammatory process. World Allergy Organization 2010-08-15 /pmc/articles/PMC3651149/ /pubmed/23282714 http://dx.doi.org/10.1097/WOX.0b013e3181ecd8ae Text en Copyright ©2010 World Allergy Organization; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Invited Review Derycke, Lara Pérez-Novo, Claudina Van Crombruggen, Koen Corriveau, Marie-Noëlle Bachert, Claus Staphylococcus aureus and Chronic Airway Disease |
title | Staphylococcus aureus and Chronic Airway Disease |
title_full | Staphylococcus aureus and Chronic Airway Disease |
title_fullStr | Staphylococcus aureus and Chronic Airway Disease |
title_full_unstemmed | Staphylococcus aureus and Chronic Airway Disease |
title_short | Staphylococcus aureus and Chronic Airway Disease |
title_sort | staphylococcus aureus and chronic airway disease |
topic | Invited Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651149/ https://www.ncbi.nlm.nih.gov/pubmed/23282714 http://dx.doi.org/10.1097/WOX.0b013e3181ecd8ae |
work_keys_str_mv | AT deryckelara staphylococcusaureusandchronicairwaydisease AT pereznovoclaudina staphylococcusaureusandchronicairwaydisease AT vancrombruggenkoen staphylococcusaureusandchronicairwaydisease AT corriveaumarienoelle staphylococcusaureusandchronicairwaydisease AT bachertclaus staphylococcusaureusandchronicairwaydisease |